90472-36-9

Upstream product

• 57707-75-2 2-pyridinal-1-phenylethylimine 
• 1121-60-4 pyridine-2-carbaldehyde 
• 618-36-0 rac-methylbenzylamine 
• 1215021-07-0 1[(S)-α-(methylbenzylamino)]-1-(R)-(2-pyridyl)-methyl-H-phosphinic acid 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 38010-70-7 (S)-1-phenyl-N-[(pyridin-2-yl)methylene]ethanamine 
• 95341-88-1 (S)-1-phenyl-N-((E)-pyridin-2-ylmethylene)ethanamine 

Downstream Products

• 1215021-10-5 N-(2-pyridylmethyl)-(S)-α-methylbenzylamine oxalate 
• 98965-27-6 (S)-N-(diphenylphosphino)-N-(1-phenylethyl)-2-pyridinemethaneamine 
• 1612791-84-0 C₁₄H₁₆Cl₂N₂Pd 

Relevant academic research and scientific papers

Synthesis and structures of copper(II) complexes containing N,N-bidentate N-substituted phenylethanamine derivatives as pre-catalysts for heterotactic-enriched polylactide

A series of Cu(II) complexes, [LnCuCl2]2 (Ln = (S)-N-((1H-pyrazol-1-yl)methyl)-1-phenylethanamine (L1), (S)-N-((3,5-dimethyl-1H-pyrazol-1-yl)methyl)-1-phenylethanamine (L2) and (S)-1-phenyl

Deciphering preferred geometries of pyridylmethylamines-based complexes: A robust strategy combining NMR, DFT and X-ray

The preparation of pyridylmethylamines (pma)-ZnBr2 and -CoBr2 complexes is described. Accurate structural informations in both solution and solid state have been obtained using an approach combining advanced NMR such as pure shift gr

Synthesis and characterization of aminopyridine iron(ii) chloride catalysts for isoprene polymerization: Sterically controlled monomer enchainment

In this study, a series of 2-R-6-(1-(alkylamino)methyl)pyridine-iron complexes [alkyl: (CPh3) Fe1H; (CHPh2) Fe2H; (CHPh2) Fe3Me; (CHMePh) Fe4H; (CH2Ph) Fe5H; (CHMe2) Fe6H; (C6H11) Fe7H; (CH2(4-OMe)Ph) Fe8H; (CH2(4-CF3)Ph) Fe9H; (CH2(2,4,6-Me3)Ph) Fe10H; (CH2Ph) Fe11Me] were synthesized and well characterized by ATR-IR spectroscopy, HRMS spectroscopy and elemental analysis. In addition, Fe3Me, Fe4H, Fe7H and Fe11Me were characterized by X-ray diffraction analysis: Fe3Me and Fe11Me adopted distorted tetrahedral geometries in the solid state while Fe4H and Fe7H were found in dimeric or polymeric forms respectively in which chlorides acted as bridging ligands. The catalytic capacities of these iron complexes were investigated for isoprene polymerization. Upon activation with a MAO cocatalyst, the catalytic activities of complexes varied as a function of the steric and electronic influences of substituents. In general, the catalysts bearing the least steric groups and electron-withdrawing groups exhibited relatively high activities. An outstanding activity of 190.6 × 104 g·mol-1·h-1 was obtained by Fe5H [CH2Ph]. Moreover, changes in the steric hindrance around the metal center showed a notable effect on the selectivity of monomer enchainment. In particular, most of the polymers obtained by these complexes bearing flexible frameworks were in favor of 3,4-enchainment.

Compositions for reductive aminations utilizing supported tricarboxyborohydride reagents and methods of using the same

A modified solid-support for use as a supported reagent for use in reduction reactions, including reductive amination comprising a solid-support having an tetrasubstituted ammonium cation species ionically bonded to a borohydride anion species extending therefrom having the general formula: wherein P is a solid-support, S is a spacer group selected from the group consisting of alkylene, {including —(CH2)n—}, alkyleneoxy {including -0(CH2)n—}, alkylenethio {including —S(CH2)n—} and alkylenecarboxy, {including —O(O)C—(CH2)n—}, n=2-16. R1, R2, R3 and R are each independently selected from the group consisting of alkyl, cycloalkyl, haloalkyl and aryl. Y equals 1, 2 or 3. H is hydrogen or deuterium.

Aminophosphinic acids in a pyridine series, Part 2: Synthesis of 2-, 3-, and 4-pyridyl derivatives of 1-(Benzylamino)-methyl-H-phosphinic Acids

New 2-pyridyl, 3-pyridyl, and 4-pyridyl derivatives of 1-[N-(benzyl)amino]- methyl-H-phosphinic acid were prepared by the addition of bis(trimethylsilyl) phosphonite to the corresponding imines and subsequent methanolysis of the addition products. Treatment of the 2-pyridyl- and 1-(4-pyridyl)-1-(benzylamino) -methyl-H-phosphinic acids with aqueous mineral acids leads to cleavage and formation of the corresponding secondary amines and phosphorous acid (H3PO3).

ASYMMETRISCHE KATALYSEN. XXIV. CROSS-COUPLING VON 1-PHENYLETHYLGRIGNARD UND VINYLBROMID MIT Ni-KATALYSATOREN OPTISCH AKTIVER P/N-LIGANDEN

Sixteen new N/N, P/N, and P/P chelate ligands, together with NiCl2, were used as in-situ catalysts for the enantioselective cross-coupling of 1-phenylethylgrignard and vinylbromide.The N/N ligands give no optical yield in the formation of the product 3-ph

Asymmetric Catalyses, 23. Optically Active Aminophosphanes - Synthesis and Use in the Rh-Catalyzed Enantioselective Hydrosilylation

New optically active P,N-ligands 6-15 were prepared by reaction of pyrrolimines, -amines, and pyridamines 1-5 with chlorophosphanes.With NEt3 as HCl scavenger the amine nitrogen NH groups were phosphinated selectively. n-BuLi as a base yielded a product mixture containing pyrrole nitrogen-phosphinated and doubly phosphinated compounds which could be separated by chromatography.On reaction with 2, the new P,N-ligands formed stable chelate complexes.In situ-catalysts from the optically active ligands 6-15 and 2 as well as the isolated Rh complexes 16-19 were used in the enantioselective hydrosilylation of acetophenone with diphenylsilane.Conversion and optical induction (up to 19.6percentee) in the formation of (+)- and (-)-phenylethanol depended on the Rh : ligand ratio, the Rh : substrate ratio, the reaction temperature, and the solvent.

Asymmetric Catalyses, 14. Enantioselective Hydrosilylation of Prochiral Ketones with Rh- and Pt-Complexes of Optically Active N-Chelate Ligands

N-chelate ligands with a lateral chiral center, which derive from optically active primary amines, amino acids, and amino acid derivatives, catalyze in Rh and Pt complexes the enantioselective hydrosilylation of acetophenone, benzyl methyl ketone, and tert-butyl methyl ketone with diphenyl- and 1-naphthylphenylsilane.The ketones are transformed into the corresponding silyl ethers which on hydrolysis yield the alcohols 1-phenylethanol, 1-phenyl-2-propanol and 3,3-dimethyl-2-butanol. 37 N ligands 1 - 37 with 2 (I) and K (XX) as well as 21 isolated complexes II - XIX and XXI - XXIII are tested.The best optical inductions exceed considerably those which were obtained with optically active phosphane containing catalysts used up to now.