90472-41-6Relevant academic research and scientific papers
Crystal Structures and Spin-Crossover Behavior of Iron(II) Complexes with Chiral and Racemic Ligands
Sekimoto, Yusuke,Karim, Mohammad Razaul,Saigo, Naoto,Ohtani, Ryo,Nakamura, Masaaki,Hayami, Shinya
, p. 1049 - 1053 (2017)
Chiral iron(II) complexes, [Fe{(R)-L}2(NCS)2] (1) and [Fe{(S)-L}2(NCS)2] (2), and racemic complex [Fe(rac)-L)2(NCS)2] (3) {L = α-methyl-N-(2-pyridinylmethylene)cyclohexanemethanamine} were synthesized. Their structures and magnetic properties were investigated by X-ray crystallography, magnetic susceptibility measurements, and M?ssbauer spectroscopy. Complexes 1 and 2 crystallize in the trigonal system with space group P3121 and P3221, respectively. All complexes exhibit spin-crossover (SCO) behavior and light induced excited spin state trapping (LIESST) effects at 532 nm. Complexes 1 and 2 show similar gradual SCO behavior, and complex 3 shows more gradual SCO, which seems to be a result of the different crystal packing, as complex 3 is the symmetric isomer but 1 and 2 are asymmetric.
Synthesis and application of new iminopyridine ligands in the enantioselective palladium-catalyzed allylic alkylation
Solinas, Maurizio,Sechi, Barbara,Chelucci, Giorgio,Baldino, Salvatore,Pedro, José R.,Blay, Gonzalo
, p. 73 - 77 (2014/03/21)
A variety of iminopyridines were obtained by condensation of chiral amines with pyridine-2-carboxaldehyde and quinoline-8-carbaldehyde, or of aminoalkylpyridine derivatives with chiral ketones. These ligands were assessed in the enantioselective palladium
Synthesis and application of new iminopyridine ligands to enantioselective copper(II)-catalyzed Henry reaction
Solinas, Maurizio,Sechi, Barbara,Baldino, Salvatore,Chelucci, Giorgio
, p. 206 - 212 (2013/08/15)
Chiral iminopyridines obtained by reaction between a variety of chiral amines and pyridyl aldehydes or ketones were assessed as catalysts in the enantioselective Henry reaction between nitromethane and 2-methoxybenzaldehyde in the presence of copper(II) a
A facile circular dichroism protocol for rapid determination of enantiomeric excess and concentration of chiral primary amines
Nieto, Sonia,Dragna, Justin M.,Anslyn, Eric V.
experimental part, p. 227 - 232 (2010/03/05)
A protocol for the rapid determination of the absolute configuration and enantiomeric excess (ee) of α-chiral primary amines with potential applications in asymmetric reaction discovery has been developed. The protocol requires derivatization of α-chiral primary amines through condensation with pyridine carboxaldehyde to quantitatively yield the corresponding imine. The Cu1 complex with 2,2′-bis (diphenylphosphino)-l,l'- dinaphthyl (BINAP-Cu1) with the imine yields a metal-to-ligand charge-transfer (MLCT) band in the visible region of the circular dichroism (CD) spectrum upon binding. Diastereomeric hostguest complexes give CD signals of the same signs but different amplitudes, allowing for differentiation of enantiomers. Processing the primary optical data from the CD spectrum with linear discriminant analysis (LDA) allows for the determination of the absolute configuration and identification of the amines, and processing with a super-vised multilayer perceptron artificial neural network (MLP-ANN) allows for the simultaneous determination of the ee and concentration. The primary optical data necessary to determine the ee of unknown samples is obtained in two minutes per sample. To demonstrate the utility of the protocol in asymmetric reaction discovery, the ee values and concentrations for an asymmetric metal-catalyzed reaction are determined. The potential of the application of this protocol in high-throughput screening (HTS) of ee is discussed.
