90473-00-0

Usage

Chemical Properties

Yellow Liquid

Uses

A 3-carboxy homolog of AMPA.

InChI:InChI=1/C14H23NO3/c1-5-18-12(16)8-15-11-7-9-6-10(13(9,2)3)14(11,4)17/h9-10,17H,5-8H2,1-4H3/b15-11-/t9-,10-,14-/m0/s1

Upstream product

• 1845-25-6 (1S,2S,5S)-(-)-2-hydroxypinan-3-one 
• 459-73-4 GlyOEt*HCl 
• 7785-70-8 (+)-α-pinene 

Downstream Products

• 35597-44-5 L-phosphinothricin 
• 73679-07-9 (S)-(+)-phosphinothricin 
• 92812-82-3 6-<(18)F>fluoro-L-DOPA 

Relevant academic research and scientific papers

A four-step synthesis of erythro-m-chloro-3-hydroxytyrosine ethyl ester enantiomerically pure

Pure erythro-m-chloro-3-hydroxytyrosine having the (2R,3R) configuration, a residue of Vancomycin and Aridicin A, has been prepared in 4 steps using an aldol addition involving a directly generated titanium enolate derived from a chiral iminoglycinate. (+)-Hydroxypinanone was used as a recoverable chiral auxiliary. The (2S,3S)-erythro isomer will be, of course, available from (-)-hydroxypinanone.

ASYMMETRIC SYNTHESIS OF (+)-PHOSPHINOTHRICIN and (+)-2-AMINO-4-PHOSPHONOBUTYRIC ACID

Asymmetric synthesis of (+)-phosphinothricin, (+)-2-amino-4-phosphono-butyric acid, and their enantiomers has been achieved by the Michael addition of chiral glycine Schiff bases to vinyl phosphorus compounds.