904744-77-0Relevant articles and documents
Metal-catalyzed cycloisomerization of enyne functionalities via a 1,3-alkylidene migration
Lin, Ming-Yuan,Das, Arindam,Liu, Rai-Shung
, p. 9340 - 9341 (2007/10/03)
We report a new metal-catalyzed 6-endo-dig cyclization of cis-4,6-dien-1-yn-3-ols, which produces substituted benzene and naphthalene derivatives with structural reorganization. In this process, we observe a 1,3-alkylidene migration via cleavage of the olefin double bond of the starting substrates. The ease and reliability of this cyclization are manifested by its compatibility with a wide array of diverse substrates and several π-alkyne activators, including PtCl2, Zn(OTf)2, AuCl, and AuCl3. Copyright