90481-37-1

Usage

Uses

Used in Pharmaceutical Industry:
2-(benzo[d]thiazol-2-yl)-5-broMophenol is used as a pharmaceutical intermediate for the synthesis of various drugs. Its unique structure and potential biological activities make it a promising candidate for the development of new therapeutic agents.
Used in Biochemical Research:
2-(benzo[d]thiazol-2-yl)-5-broMophenol is used as a biochemical reagent in various research applications. Its presence in the structure allows for the study of its interactions with other molecules and its potential role in biological processes.
Used in Synthesis of Other Compounds:
2-(benzo[d]thiazol-2-yl)-5-broMophenol is used as a key building block in the synthesis of other compounds with diverse applications. Its unique structure and functional groups make it a valuable component in the development of new chemical entities.
Used in Drug Design and Development:
2-(benzo[d]thiazol-2-yl)-5-broMophenol is used as a scaffold in drug design and development. Its benzothiazole moiety and bromine substitution provide a foundation for the creation of new drugs with improved pharmacological properties and potential therapeutic applications.

Upstream product

• 19654-19-4 2-(4-bromophenyl)benzothiazole 
• 1122-91-4 4-bromo-benzaldehyde 
• 137-07-5 2-amino-benzenethiol 
• 22532-62-3 4-bromosalicylaldehyde 
• 1666-28-0 4-bromosalicylic acid 

Relevant academic research and scientific papers

Linear and nonlinear photophysics and bioimaging of an integrin-targeting water-soluble fluorenyl probe

Linear photophysical characterization and two-photon absorption (2PA) properties of a new water-soluble fluorene derivative, 3-(9-(2-(2-methoxyethoxy) ethyl)-2,7-bis{3-[2-(polyethyleneglycol-550-monomethylether-1-yl)]-4-(benzo[d] thiazol-2-yl)styryl}-9H-f

Direct Oxygenation of C-H Bonds through Photoredox and Palladium Catalysis

This report presents the oxygenation of C-H bonds via the merger of photocatalysis and Pd catalysis. Herein, we describe the utilization of a photocatalyst to oxidize an organopalladium(II) intermediate to high-valent PdIII or PdIV intermediates, which promotes the formation of C-O bonds. The demonstrated method works efficiently with various directing groups, such as oxime ether and benzothiazole. The applicability of this direct C-O bond formation method is shown by synthesizing several metal complexes of 2-(benzo[d]thiazol-2-yl)phenol that can be used in organic light-emitting diodes and pharmaceuticals.

Benzoazacyclo derivative, preparation method and application thereof, and photoluminescence lubricating grease

The invention provides a benzoazacyclo derivative, a preparation method and application thereof, and photoluminescence lubricating grease containing the benzoazacyclo derivative. The structure of thebenzoazacyclo derivative is shown in the specification,

Rational design of the benzothiazole-based fluorescent scaffold for tunable emission

The 2-(2-hydroxyphenyl)-benzothiazole (HBT) fluorophore has attracted considerable attention due to its excited-state intramolecular proton transfer (ESIPT) based emission and its large Stokes shift. However, this fluorophore possesses several disadvantag

Metallaphotoredox-Mediated Csp2-H Hydroxylation of Arenes under Aerobic Conditions

The direct hydroxylation of 2-arylpyridines and 2-arylbenzothiazoles via the merger of organic photoredox and metal catalysis is reported where 4CzIPN is used as the visible-light photocatalyst and Pd(OAc)2 as the metal catalyst. This method has been employed to synthesize organic molecules exhibiting excited-state intramolecular proton transfer properties for generating tunable luminescence responses.

Excited State Intramolecular Proton Transfer in Ethynyl-Extended Regioisomers of 2-(2′-Hydroxyphenyl)benzothiazole: Effects of the Position and Electronic Nature of Substituent Groups

Although the organic dyes based on excited state intramolecular proton transfer (ESIPT) mechanism have attracted significant attention, the structure-property relationship of ESIPT dyes needs to be further exploited. In this paper, three series of ethynyl-extended regioisomers of 2-(2′-hydroxyphenyl)benzothiazole (HBT), at the 3′-, 4′- and 6-positions, respectively, have been synthesized. Changes in the absorption and emission spectra were correlated with the position and electronic nature of the substituent groups. Although 4′- and 6-substituted HBT derivatives exhibited absorption bands at longer wavelengths, the keto-emission of 3′-substituted HBT derivatives was found at a substantially longer wavelength. The gradual red-shifted fluorescence emission was found for 3′-substituted HBT derivatives where the electron-donating nature of substituent group increased, which was opposite to what was observed for 4′- and 6-substituted HBT derivatives. The results derived from the theoretical calculations were in conformity with the experimental observations. Our study could potentially provide experimental and theoretical basis for designing novel ESIPT dyes that possess unique fluorescent properties.

AIE active triphenylamine-benzothiazole based motifs: ESIPT or ICT emission

Two novel donor-π bridge-acceptor compounds containing excited state intramolecular proton transfer (ESIPT) and non-ESIPT units based on triphenylamine-benzothiazole were synthesized via Suzuki coupling reaction. Their photophysical properties were studie

Synthesis of 2-substituted benzimidazoles and benzothiazoles using Ag2CO3/Celite as an efficient solid catalyst

An efficient and simple approach for the synthesis of 2-substituted benzimidazoles and benzothiazoles through a coupling of 1,2-phenylenediamines and 2-aminothiophenols with variety of aryl aldehydes in ethanol at 70 °C using Ag2CO3/Celite as solid catalyst is described. The procedure features short reaction time, excellent yields and simple workup.

New organoboron compounds and the use thereof

PURPOSE: An organoboron compound with a blue light emitting property is provided to manufacture and realize an organic light emitting diode(OLED). CONSTITUTION: An organoboron compound or a salt thereof is denoted by chemical formula 1. The compound emits

Solid-state Fluorescent Photophysics of Some 2-Substituted Benzothiazoles

The solid-state fluorescence properties of a series of benzothiazoles with phenyl, napthalene, and coumarin moieties substituted at the 2-position have been investigated.The necessity for a 2'-OH substituent for fluorescence has been confirmed and the effects of further substitution in the 2-phenyl ring are reported.