904833-94-9

Upstream product

• 904833-86-9 5-methyl-5-propyl-2-vinyl-tetrahydro-furan-3-ol 
• 824-94-2 p-methoxybenzyl chloride 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 904833-80-3 2-methyl-1-(3-vinyl-oxiranyl)-pentan-2-ol 
• 209118-78-5 (2S)-4-(4-methoxyphenoxy)-2-methylbutane-1,2-diol 
• 169310-73-0 1-methoxy-4-((3-methylbut-3-en-1-yl)oxy)benzene 
• 763-32-6 2-methyl-1-buten-4-ol 
• 904833-37-0 triisopropyl-{1-[2-(4-methoxy-phenoxy)-ethyl]-1-methyl-butoxy}-silane 
• 904833-22-3 4-(4-methoxy-phenoxy)-2-methyl-2-triisopropylsilanyloxy-butan-1-ol 
• 904834-14-6 triisopropyl-{1-[2-(4-methoxy-phenoxy)-ethyl]-1-methyl-but-2-enyloxy}-silane 
• 904834-22-6 5-methyl-5-triisopropylsilanyloxy-oct-2-enoic acid ethyl ester 
• 904833-30-3 4-(4-methoxy-phenoxy)-2-methyl-2-triisopropylsilanyloxy-butyraldehyde 
• 904833-60-9 [3-(2-methyl-2-triisopropylsilanyloxy-pentyl)-oxiranyl]-methanol 
• 904833-73-4 triisopropyl-[1-methyl-1-(3-vinyl-oxiranylmethyl)-butoxy]-silane 

Downstream Products

• 826995-05-5 2-{(2S,3R,5R)-3-[(4-methoxybenzyl)oxy]-5-methyl-5-propyltetrahydrofuran-2-yl}ethanol 

Relevant academic research and scientific papers

A route to the tetrahydrofuran segment of amphidinolides X and Y, and its quaternary-carbon epimer

A short approach to the tetrahydrofuran fragment of amphidinolides X and Y has been developed through the combination of iterative Sharpless asymmetric epoxidations, Pd-catalyzed regioselective hydrogenolysis of a 4,5-epoxy-2-alkenoate and the disfavored 5-endo-tet ring closure of a β-hydroxy epoxide promoted by a double bond adjacent to the epoxide function. Georg Thieme Verlag Stuttgart.

A new synthesis of tetrahydrofuran fragment of amphidinolides X and Y

A new synthesis of the tetrasubstituted tetrahydrofuran fragment of the marine secondary metabolites amphidinolides X and Y is described. The oxygenated chiral quaternary carbon was assembled by asymmetric dihydroxylation in high enantioselectivity and th