90486-42-3Relevant academic research and scientific papers
The Reformatsky Type Reaction of Gilman and Speeter in the Preparation of Valuable β-Lactams in Carbapenem Synthesis: Scope and Synthetic Utility
Palomo, Claudio,Cossio, Fernando P.,Arrieta, Ana,Odriozola, Jose M.,Oiarbide, Mikel,Ontoria, Jesus M.
, p. 5736 - 5745 (2007/10/02)
The preparation of apppropriately substituted 3-alkyl β-lactams from the Reformatsky type reaction of Gilman and Speeter is described.Treatment of Schiff bases derived from α-methylcinnamaldehyde and amines with ethyl α-bromobutyrate or ethyl α-bromoisova
β-Lactam Formation by Ultrasound-promoted Reformatsky Type Reaction
Bose, Ajay K.,Gupta, Kavita,Manhas, M. S.
, p. 86 - 87 (2007/10/02)
Ultrasound was found to promote the reaction between ethyl bromoacetate, zinc, and a Schiff base such that an excellent yield of β-lactams was obtained in a few hours at room temperature.
