90490-53-2 Usage
Chemical structure
A phosphorus-containing heterocyclic compound with a five-membered nitrogen-containing ring and two phenyl groups attached to the second and third carbon atoms.
Functional groups
a. Phosphorus atom
b. Nitrogen-containing ring
c. Phenyl groups
Application
Commonly used in organic synthesis and medicinal chemistry.
Potential therapeutic use
Studied for its potential as a therapeutic agent, particularly in the treatment of cancer and other diseases.
Biological activity
Its chemical properties and biological activity make it a valuable tool in drug discovery and development.
Solubility
Not mentioned in the provided material, but generally, similar compounds may have varying solubility in organic solvents.
Stability
Not mentioned in the provided material, but generally, similar compounds may be sensitive to air, light, or moisture, and require proper storage conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 90490-53-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,4,9 and 0 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 90490-53:
(7*9)+(6*0)+(5*4)+(4*9)+(3*0)+(2*5)+(1*3)=132
132 % 10 = 2
So 90490-53-2 is a valid CAS Registry Number.
90490-53-2Relevant academic research and scientific papers
Organphosphorus Compounds. XVIII. Synthesisi of 2-Phenyl-2,3-dihydro-1H-1,2-benzazaphosphole 2-Sulfide by Pyrolysis of (2-Aminobenzyl)phenyldithiophosphonic Acid
Collins, David J.,Drygala, Peter F.,Swan, John M.
, p. 2095 - 2110 (2007/10/02)
Reaction of 2-phthalimidobenzyl bromide (12b) with the dialkyl phenylphosphonites (13a-c) afforded the corresponding alkyl phosphinates (14a-c) which upon hydrazinolysis yielded the respective (2-aminobenzyl)phenylphosphinates (16a-c).Reduction of the phosphinates (16a) or (16b) with lithium aluminium hydride gave (2-aminobenzyl)phenylphosphine (15), characterized by its conversion into crystalline 2,3-diphenyl-1,2,3,4-tetrahydro-1,3-benzazaphosphorine (18). (2-Aminobenzyl)phenylphosphine (15) was heated with sulfur in benzene under reflux for 30 min to give 80percent of (2-aminobenzyl)phenyldithiophosphinic acid (20) which when heated between 100-200 deg in vacuum underwent elimination of hydrogen sulfide to yield 2-phenyl-2,3-dihydro-1H-1,2-benzazaphosphole 2-sulfide (22a).Several other new phosphorus compounds are described.An attempt to prepare a 1H-1,2-benzazaphosphole derivative by photolysis of methyl benzylphosphonic azide (7) was unsuccessful.
