904913-16-2Relevant academic research and scientific papers
Synthesis of benzoazocines from substituted tetrahydroisoquinolines and activated alkynes in a tetrahydropyridine ring expansion
Voskressensky, Leonid G.,Listratova, Anna V.,Borisova, Tatiana N.,Alexandrov, Grigoriy G.,Varlamov, Alexey V.
, p. 6106 - 6117 (2008/09/17)
Tetrahydroisoquinolines underwent tandem piperidine ring enlargement in the presence of activated alkynes in acetonitrile or methanol, producing tetrahydrobenzo[d]azocines in high yields. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.
Tandem enlargement of the tetrahydropyridine ring in 1-aryl-tetrahydroisoquinolines using activated alkynes-a new and effective synthesis of benzoazocines
Voskressensky, Leonid G.,Borisova, Tatiana N.,Listratova, Anna V.,Kulikova, Larisa N.,Titov, Alexander A.,Varlamov, Alexey V.
, p. 4585 - 4589 (2007/10/03)
Tetrahydroisoquinolines 3a-e underwent piperidine ring enlargement under the action of activated alkynes, giving benzoazocines 4, 5 and 7-11 in high yields.
