904915-11-3

Upstream product

• 904915-03-3 (S,E)-1-Benzyl-4-(benzyloxy)-5-butylidenepyrrolidin-2-one 
• 67-56-1 methanol 
• 187091-57-2 (S)-1-Benzyl-4-benzyloxy-5-butyl-5-hydroxy-pyrrolidin-2-one 
• 170711-05-4 (S)-1-benzyl-3-(benzyloxy)pyrrolidine-2,5-dione 

Relevant academic research and scientific papers

Complementary stereocontrolled approaches to 2-pyrrolidinones bearing a vicinal amino diol subunit with three continuous chiral centers: A formal asymmetric synthesis of (-)-detoxinine

(Chemical Equation Presented) We report herein two stereocomplementary approaches to erythro/trans and threo/cis vicinal amino diol subunits containing 2-pyrrolidinones (9 and 10) starting from the known enamides 7, easily available from malimides. The fi

A versatile approach to protected (4S,5R)-4-hydroxy-5-(α- hydroxyalkyl)-2-pyrrolidinones

Starting from (S)-N,O-dibenzylmalimide (7), a versatile four-step approach to (4S,5R)-N-benzyl-4-benzyloxy-5-(α-hydroxyalkyl)-2-pyrrolidinones 9 is reported. The method consists of Grignard reagent addition, p-toluenesulfonic acid monohydrate-mediated deh