90515-49-4Relevant academic research and scientific papers
3-Amidocoumarins as Potential Multifunctional Agents against Neurodegenerative Diseases
Matos, Maria Jo?o,Rodríguez-Enríquez, Fernanda,Borges, Fernanda,Santana, Lourdes,Uriarte, Eugenio,Estrada, Martín,Rodríguez-Franco, María Isabel,Laguna, Reyes,Vi?a, Dolores
, p. 2071 - 2079 (2015/12/23)
Monoamine oxidase (MAO) generates reactive oxygen species (ROS), which cause neuronal cell death, causing neurodegeneration. Agents that are able to concurrently inhibit MAO and scavenge free radicals represent promising multifunctional neuroprotective ag
Synthesis and biological activity of simplified denoviose-coumarins related to novobiocin as potent inhibitors of heat-shock protein 90 (hsp90)
Radanyi, Christine,Le Bras, Gaelle,Messaoudi, Samir,Bouclier, Celine,Peyrat, Jean-Francois,Brion, Jean-Daniel,Marsaud, Veronique,Renoir, Jack-Michel,Alami, Mouad
, p. 2495 - 2498 (2008/09/20)
A new series of coumarin inhibitors of hsp90 lacking the noviose moiety as well as substituents on C-7 and C-8 positions of the aromatic ring was synthesised and their hsp90 inhibitory activity has been delineated: for example, their capacity to induce th
Synthesis, Antibacterial and Antifungal Activity of 4-Hydroxycoumarin Derivatives, Analogues of Novobiocin
Patonay, T.,Litkei, Gy.,Bognar, R.,Erdei, J.,Miszti, Cecilia
, p. 86 - 91 (2007/10/02)
3-Acylamino-, -arylsulfonylamino-, -(N'-arylureido)-, -arylideneamino- and -arylcarbamoyl-4-hydroxycoumarins have been synthesized and tested for antibacterial and antifungal activity. 3-Arylcarbamoyl-4-hydroxycoumarins have been shown to possess signific
