90524-84-8

Usage

InChI:InChI=1/C10H11N3O7/c14-1-2-5(15)6(16)8(19-2)3-7-4(13-12-3)9(17)11-10(18)20-7/h2,5-6,8,14-16H,1H2,(H,12,13)(H,11,17,18)/t2-,5-,6-,8+/m1/s1

Upstream product

• 59252-17-4 2′,3′-O-isopropylidenepyrazofurin 
• 530-62-1 1,1'-carbonyldiimidazole 
• 30868-30-5 pyrazofurin 
• 83686-32-2 ethyl 4-hydroxy-3-(2′,3′-O-isopropylidene-5′-O-trityl-β-D-ribofuranosyl)pyrazole-5-carboxylate 
• 83686-33-3 4-hydroxy-3-(2′,3′-O-isopropylidene-5′-O-trityl-β-D-ribofuranosyl)pyrazole-5-carboxamide 
• 90524-78-0 3-(2',3'-O-isopropylidene-5'-O-trityl-β-D-ribofuranosyl)-1H,6H-pyrazolo<3,4-e><1,3>oxazine-5,7-dione 

Relevant academic research and scientific papers

Synthetic approaches to the guanosine and xanthosine analogues 5-amino-3-β-D-ribofuranosylpyrazolo[3,4-e][1,3]oxazin-7-one and 3-β-D-ribofuranosylpyrazolo[3,4-e][1,3]oxazine-5,7-dione and studies of their antitumor potential

5-Amino-3-β-D-ribofuranosylpyrazolo[3,4-e][1,3]oxazin-7-one has been synthesized via cyclization of the appropriately protected pyrazofurin derivatives and subsequent transformations of the hetorocyclic moiety. This guanosine analogue was marginally cytot

Synthesis of Pyrazofurin and its Analogues

Pyrazofurin and its analogues have been synthesized fron ribosyl β-keto acid derivatives, which can be readily prepared by Wittig reaction of the protected D-ribose with phosphoranes.Reaction of 2,3-O-isopropylidene-5-O-trityl-α- and β-D-ribose (6) with 3