905286-72-8

Upstream product

• 904893-24-9 (-)-(2R,3R,4R)-1,3,4-tris(benzyloxy)-5-oxopentan-2-yl methanesulfonate 
• 904893-23-8 (3S,4R,5R)-5-methanesulfonyloxy-3,4,6-tribenzyloxy-1-hexene 
• 201290-06-4 3,4,6-tri-O-benzyl-1,2-dideoxy-D-xylo-hex-1-enitol 
• 16838-89-4 2,3,5-tri-O-benzyl-D-xylofuranose 
• 120186-59-6 (4-(benzyloxy)phenyl)magnesium bromide 
• 96192-07-3 2,3,5-tri-O-benzyl-L-arabinofuranose 
• 913365-65-8 C₃₂H₄₂INO₄Si 
• 904893-22-7 (2S,3S,4S)-3,4-bis(benzyloxy)-2-(benzyloxymethyl)-3,4-dihydro-2H-pyrrole-1-oxide 
• 913365-66-9 (2S,3S,4S,5S)-3,4-Bis-benzyloxy-2-benzyloxymethyl-5-(4-benzyloxy-phenyl)-pyrrolidine 
• 904893-28-3 (2S,3S,4S,5S)-2-benzyloxymethyl-3,4-dibenzyloxy-5-(4-benzyloxyphenyl)-N-hydroxy-pyrrolidine 
• 6793-92-6 p-benzyloxyphenylbromide 
• 913365-64-7 (2S,3S,4S)-2,3,5-Tris-benzyloxy-4-hydroxy-pentanal oxime 

Relevant academic research and scientific papers

Radicamines A and B: Synthesis and revision of the absolute configuration

Starting from D-xylose, enantioselective syntheses of 1 and 2, the proposed structures for radicamines A and B, were accomplished. Both 1H and 13C NMR spectra of 1 and 2 were identical with those of the natural products, but the optical rotation measurements identified that 1 and 2 were actually the enantiomers of the natural radicamines A and B, respectively.

Total synthesis of (-)-radicamine B

The synthesis of a chiral cyclic nitrone with l-arabino configuration and its application in the total synthesis of radicamine B is reported. An agreement in the spectral data with natural radicamine B but specific rotation with an opposite sign warranted