905294-00-0Relevant academic research and scientific papers
BIVALENT SMAC MIMETICS AND THE USES THEREOF
-
Page/Page column 89-90, (2008/06/13)
The invention relates to bivalent mimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these mimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosi
Design and synthesis of a 1,5-diazabicyclo[6,3,0] dodecane amino acid derivative as a novel dipeptide reverse-turn mimetic
Peng, Yuefeng,Sun, Haiying,Wang, Shaomeng
, p. 4769 - 4770 (2007/10/03)
N-Boc-1,5-diazabicyclo[6,3,0] dodecane amino acid tert-butyl ester (3), designed as a novel dipeptide reverse-turn mimetic, was synthesized in a concise method from the known compound 4 in an overall yield of 47%.
