1056941-53-7

Upstream product

• 905293-99-4 YP-237P 
• 65710-57-8 3-{[(benzyloxy)carbonyl]amino}-N-(tert-butoxycarbonyl)-L-alanine 
• 90741-40-5 tert-butyl (2R,5R)-1-benzyl-5-(2-hydroxyethyl)pyrrolidine-2-carboxylate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 1056941-54-8 1-benzyl-5-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-pyrrolidine-2-carboxylic acid tert-butyl ester 

Downstream Products

• 905294-00-0 1-(3-benzyloxycarbonylamino-2-tert-butoxycarbonylamino-propionyl)-5-(2-hydroxy-ethyl)-pyrrolidine-2-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

BIVALENT SMAC MIMETICS AND THE USES THEREOF

The invention relates to bivalent mimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these mimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosi

Design and synthesis of a 1,5-diazabicyclo[6,3,0] dodecane amino acid derivative as a novel dipeptide reverse-turn mimetic

N-Boc-1,5-diazabicyclo[6,3,0] dodecane amino acid tert-butyl ester (3), designed as a novel dipeptide reverse-turn mimetic, was synthesized in a concise method from the known compound 4 in an overall yield of 47%.