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Usage

Uses

Used in Pharmaceutical Research:
2-BOC-Aminomethyl-phenylboronic acid pinacol ester is used as an intermediate chemical compound for new drug synthesis. Its role is crucial in the development of novel pharmaceuticals, where it serves as a building block for creating more complex molecules with potential therapeutic applications.
Used in Organic Chemistry:
In the field of organic chemistry, 2-BOC-Aminomethyl-phenylboronic acid pinacol ester is utilized as an intermediate for studying compound interactions and behaviors. Its reactivity allows researchers to explore various chemical reactions and mechanisms, contributing to a deeper understanding of organic chemistry principles.
Used in Scientific Research:
2-BOC-Aminomethyl-phenylboronic acid pinacol ester is employed as a key component in laboratory settings, where its properties are harnessed for conducting experiments and advancing scientific knowledge. Its stability and reliability make it a preferred choice for researchers working on complex chemical syntheses and analyses.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 3959-05-5 2-bromobenzylamine 
• 73183-34-3 bis(pinacol)diborane 
• 162356-90-3 N-(tert-butoxycarbonyl)-2-bromobenzylamine 

Downstream Products

• 1431959-69-1 C₂₁H₁₉N₅S 
• 1431959-84-0 C₂₁H₂₅N₅S 
• 1431959-88-4 C₁₉H₁₇N₅OS 
• 1083300-30-4 TH₀₄₃₀₆-009 
• 1121584-98-2 2-(pyridin-2-yl)benzylamine 
• 1431961-02-2 tert-butyl 2-(oxazol-4-yl)benzylcarbamate 
• 1431961-06-6 TH₀₃₈₂₁-148 
• 1431961-07-7 TH₀₄₀₉₂-008 
• 1431961-08-8 TH₀₄₀₉₂-014 
• 1431960-86-9 TH₀₄₃₀₆-003 
• 1431960-87-0 C₁₇H₂₀N₂O₂ 

Relevant academic research and scientific papers

2-METHYL-QUINAZOLINES

The present invention describes 2-methyl-quinazoline compounds of general formula (I), methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions. The 2-methyl substituted quinazoline compounds of general formula(I) effectively and selectively inhibit the Ras-Sos interaction without significantly targeting the EGFR receptor. They are therefore useful for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, such as cancer as a sole agent or in combination with other active ingredients.

CHEMICAL COMPOUNDS

The invention is directed to substituted heteroaryl derivatives. Specifically, the invention is directed to compounds according to Formula Q: wherein D, L, M, W, X, Y, and Z are defined herein. The compounds of the invention are inhibitors of DNA methyltransferase (DNMT) activity - including DNMT1, DNMT3a, or DNMT3b- and are useful in the treatment of cancer and hyperproliferative diseases. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting DNMT activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention