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Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-4-Methoxypyridine-3-carbaldehyde is utilized as an intermediate in the synthesis of pharmaceuticals, contributing to the development of new drugs and medicinal compounds. Its reactivity allows for the creation of a wide range of chemical entities that can be tailored for specific therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Chloro-4-Methoxypyridine-3-carbaldehyde serves as a key intermediate in the production of various agrochemicals. Its role in the synthesis of these compounds aids in the development of pesticides, herbicides, and other agricultural products designed to enhance crop protection and yield.
Used in Organic Compounds Synthesis:
2-Chloro-4-Methoxypyridine-3-carbaldehyde is also employed in the synthesis of organic compounds, where its unique structure and reactivity enable the formation of complex organic molecules. This makes it a crucial component in the creation of specialty chemicals and materials for various applications.

Upstream product

• 17228-69-2 2-chloro-4-methoxy-pyridine 
• 68-12-2 N,N-dimethyl-formamide 
• 34851-41-7 tetrabutyl ammonium methoxide 
• 134031-24-6 2,4-dichloro-3-pyridine Carboxaldehyde 

Downstream Products

• 1378822-82-2 (2-chloro-4-methoxypyridin-3-yl)methanol 

Relevant academic research and scientific papers

Synthesis method of 2-chloro-4-hydroxypyridine-3-formaldehyde hydrobromide

The invention discloses a synthesis method of 2-chloro-4-hydroxypyridine-3-formaldehyde hydrobromide, and belongs to the field of organic chemical synthesis. The method comprises the following steps:dissolving 2-chloro-4-methoxypyridine-3-formaldehyde in an organic solvent, and carrying out a reaction with boron tribromide under the protection of nitrogen to obtain a target product 2-chloro-4-hydroxypyridine-3-formaldehyde hydrobromide, wherein the 2-chloro-4-methoxypyridine-3-formaldehyde is synthesized by taking 2-chloro-4-methoxypyridine as a raw material in a self-made manner. The methodis simple in synthesis operation and short in process route, and the yield of the obtained product is relatively high.

2-HYDROXYMETHYL-SUBSTITUTED OREXIN RECEPTOR ANTAGONISTS

The present invention is directed to 2-hydroxymethyl compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved.

1-(PIPERIDIN-4-YL)-1H-INDOLE DERIVATIVE

The present invention provides a compound represented by the formula (1) or a pharmacologically acceptable salt thereof, or a hydrate thereof (provided that a compound in which all of R4a, R4b, and R4c are hydrogen atoms is excluded.): [wherein R1 represents a hydrogen atom, R2 represents a hydrogen atom, R3 represents the formula: wherein R4a, R4b, and R4c are the same as or different from each other and each represents a hydrogen atom, a C1-6 alkyl group or a C1-6 alkoxy group, etc.]