905587-32-8

Basic information

• Product Name: Acetamide, N-[1-(5-fluoro-2-pyrimidinyl)ethenyl]-
• Synonyms: Acetamide, N-[1-(5-fluoro-2-pyrimidinyl)ethenyl]-
• CAS NO: 905587-32-8
• Molecular Formula: C8H8FN3O
• Molecular Weight: 181.17
• Mol File: 905587-32-8.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Acetamide, N-[1-(5-fluoro-2-pyrimidinyl)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[1-(5-fluoro-2-pyrimidinyl)ethenyl]-(905587-32-8)
• EPA Substance Registry System: Acetamide, N-[1-(5-fluoro-2-pyrimidinyl)ethenyl]-(905587-32-8)

Safety Data

• Hazardous Substances Data: 905587-32-8(Hazardous Substances Data)

Upstream product

• 75-16-1 methylmagnesium bromide 
• 108-24-7 acetic anhydride 
• 38275-55-7 5- fluoropyrimidine-2-carbonitrile 

Downstream Products

• 905587-31-7 (S)-N-(1-(5-fluoropyrimidin-2-yl)ethyl)acetamide 
• 905587-30-6 (S)-tert-butyl-1-(5-fluoropyrimidin-2-yl)ethylcarbamate 
• 935667-21-3 (1S)-1-(5-fluoropyrimidin-2-yl)ethanamine monohydrochloride 
• 1079274-94-4 (S)-N-(1-(5-fluoropyrimidin-2-yl)ethyl)-3-(5-isopropoxy-1H-pyrazol-3-yl)-3H-imidazo[4,5-b]pyridin-5-amine 
• 1079275-47-0 N2-(5-ethoxy-1H-pyrazol-3-yl)-N6-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-3-nitropyridine-2,6-diamine 

Relevant articles and documents

Pyridin-2(1H)-one derivatives useful as medicaments for the treatment of myeloproliferative disorders, transplant rejection, immune-mediated and inflammatory diseases

New pyridin-2(1h)-one derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).

Heteroaryl imidazolone derivatives as jak inhibitors

New heteroaryl imidazolone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).

2-(IMIDAZ0LYLAMIN0)-PYRIDINE DERIVATIVES AND THEIR USE AS JAK KINASE INHIBITORS

The present inv ention relates to compounds of Formula (I): or a pharmaceutically acceptable salt thereof, wherein Ring A is 5- or 6-membered heteroaryl, wherein said 5- or 6-membered heteroaryl is optionally substituted on carbon with one or more R6