90563-57-8

Usage

Uses

Used in Pharmaceutical Synthesis:
5-Indolinecarboxaldehyde (7CI) serves as an intermediate in the synthesis of pharmaceutical compounds, contributing to the development of new medications and therapeutic agents. Its unique chemical structure allows it to be a key component in creating a variety of pharmaceutical products.
Used in Organic Chemical Synthesis:
As a versatile intermediate, 5-Indolinecarboxaldehyde (7CI) is employed in the synthesis of other organic chemicals. Its ability to participate in various chemical reactions makes it an essential tool for creating a wide array of organic compounds used in different industries.
Used in Chemical Research:
5-Indolinecarboxaldehyde (7CI) is utilized as a reagent in numerous chemical reactions, particularly in the field of organic chemistry. Its involvement in research helps scientists explore new reaction pathways, develop innovative synthetic methods, and enhance the understanding of chemical processes.
Used in Industrial Applications:
Beyond its role in research and pharmaceutical synthesis, 5-Indolinecarboxaldehyde (7CI) finds use in various industrial applications. Its properties make it suitable for contributing to the production of specialty chemicals, materials, and other products that require its unique characteristics.

Upstream product

• 1196-69-6 1H-indole-5-carboxaldehyde 

Relevant academic research and scientific papers

Dual-Active-Sites Design of Co@C Catalysts for Ultrahigh Selective Hydrogenation of N-Heteroarenes

The dual-active-sites Co@C catalyst provides a general powerful strategy to break the limitation of scaling relation on traditional metal surfaces and thus affords unprecedentedly selective hydrogenation of various N-heteroarenes as well as high activity and stability. A porous carbon shell not only allows H2 diffusion to Co sites for activation but also blocks accessibility of N-heteroarenes, and the hydrogenation of N-heteroarenes is achieved on carbon by the spilled hydrogen from Co sites. In addition, the presence of surface/subsurface carbon at the Co sites shows high anti-sulfur poisoning and anti-oxidant capability. Ideal heterogeneous metal hydrogenation catalysts are featured by simultaneously high activity, selectivity, and stability. Herein, we report a general yet powerful strategy to design and fabricate dual-active-sites Co@C core-shell nanoparticle for boosting selective hydrogenation of various N-heteroarenes. It can break the limitation of scaling relation on traditional metal surfaces, and thus afford unprecedentedly high selectivity, activity, and stability. Combining kinetics analysis and DFT calculations with multiple techniques directly unveil that the critical porous carbon shell with a pore size of 0.53 nm not only allows H2 diffusion to Co sites for activation and blocks accessibility of N-heteroarenes but also catalyzes hydrogenation of N-heteroarenes via hydrogen spillover from Co sites. In addition, the presence of surface/subsurface carbon at the Co sites shows high anti-sulfur poisoning and anti-oxidant capability. This work is valuable for guiding the design and manipulation of cost-effective and robust hydrogenation catalysts. Our research can provide an environmentally friendly approach to afford unprecedentedly selective N-heteroarenes hydrogenation, which will greatly reduce the resource and energy consumption and decrease the amount of waste discharge and water pollution. Therefore, these results could help in achieving the “Clean water and sanitation” goal in the 10 UN Sustainable Development Goals. Meanwhile, the products of N-heteroarenes hydrogenation are the core structural motifs in both fine and bulk chemicals, which will make our life more beautiful. Thus, our research also benefits the “Good health and well-being” goal.