905858-76-6

Basic information

• Product Name: 4-{3-amino-5-[3-tert-butoxycarbonyl-1,1-bis-(2-tert-butoxycarbonyl-ethyl)-propylcarbamoyl]-benzoylamino}-4-(2-tert-butoxycarbonyl-ethyl)-heptanedioic acid di-tert-butyl ester
• Synonyms: 4-{3-amino-5-[3-tert-butoxycarbonyl-1,1-bis-(2-tert-butoxycarbonyl-ethyl)-propylcarbamoyl]-benzoylamino}-4-(2-tert-butoxycarbonyl-ethyl)-heptanedioic acid di-tert-butyl ester
• CAS NO: 905858-76-6
• Molecular Weight: 976.259
• Mol File: 905858-76-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-{3-amino-5-[3-tert-butoxycarbonyl-1,1-bis-(2-tert-butoxycarbonyl-ethyl)-propylcarbamoyl]-benzoylamino}-4-(2-tert-butoxycarbonyl-ethyl)-heptanedioic acid di-tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{3-amino-5-[3-tert-butoxycarbonyl-1,1-bis-(2-tert-butoxycarbonyl-ethyl)-propylcarbamoyl]-benzoylamino}-4-(2-tert-butoxycarbonyl-ethyl)-heptanedioic acid di-tert-butyl ester(905858-76-6)
• EPA Substance Registry System: 4-{3-amino-5-[3-tert-butoxycarbonyl-1,1-bis-(2-tert-butoxycarbonyl-ethyl)-propylcarbamoyl]-benzoylamino}-4-(2-tert-butoxycarbonyl-ethyl)-heptanedioic acid di-tert-butyl ester(905858-76-6)

Safety Data

• Hazardous Substances Data: 905858-76-6(Hazardous Substances Data)

Upstream product

• 618-88-2 5-nitrobenzene-1,3-dicarboxylic acid 
• 13438-30-7 5-nitro-1,3-benzenedicarbonylchloride 
• 263843-49-8 4-{3-[3-tert-butoxycarbonyl-1,1-bis-(2-tert-butoxycarbonyl-ethyl)-propylcarbamoyl]-5-nitro-benzoylamino}-4-(2-tert-butoxycarbonyl-ethyl)-heptanedioic acid di-tert-butyl ester 

Relevant articles and documents

Iron binding dendrimers: A novel approach for the treatment of haemochromatosis

A range of iron binding dendrimers terminated with hexadentate ligands formed from hydroxypyridinone, hydroxypyranone, and catechol moieties have been synthesized in order to investigate their potential as clinically useful iron(III)-selective chelators capable of removing dietary iron from the gastrointestinal tract and preventing the development of iron overload typical of haemochromatosis and thalassaemia intermedia. The iron chelating abilities of these molecules have been characterized by MALDI-TOF mass spectrometry and UV spectrometry. Hydroxypyridinone-terminated dendrimers were found to possess a high affinity and selectivity for iron(III). A hydroxypyridinone-based dendrimer was demonstrated to be highly efficient at reducing the absorption of iron(III) in rat intestine. This family of dendrimers may find an application in the treatment of iron overload.