905927-08-4Relevant academic research and scientific papers
Asymmetric synthetic access to the hetisine alkaloids: Total synthesis of (+)-nominine
Peese, Kevin M.,Gin, David Y.
, p. 1654 - 1665 (2008)
A dual cycloaddition strategy for the synthesis of the hetisine alkaloids has been developed, illustrated by a concise asymmetric total synthesis of (+)-nominine (7). The approach relies on an early-stage intramolecular 1,3-dipolar cyclo-addition of a 4-o
Efficient synthetic access to the hetisine C20-diterpenoid alkaloids. A concise synthesis of nominine via oxidoisoquinolinium-1,3-dipolar and dienamine-Diels Alder cycloadditions
Peese, Kevin M.,Gin, David Y.
, p. 8734 - 8735 (2007/10/03)
A concise synthetic approach to the hetisine C20-diterpenoid alkaloids is reported. The total synthesis of (±)-nominine was accomplished in a 15-step sequence employing a dual cycloaddition strategy. Key features of the synthesis include a reve
