905975-83-9Relevant academic research and scientific papers
Discovery of protein-protein binding disruptors using multi-component condensations small molecules
Bedjeguelal, Karim,Bienayme, Hugues,Dumoulin, Antoine,Poigny, Stephane,Schmitt, Philippe,Tam, Eric
, p. 3998 - 4001 (2006)
A series of small molecule compounds interfering with the binding process of VEGF and NRP1 has been identified and further optimized. Full synthetic details as well as SAR are reported which demonstrate that expeditious MCC-based syntheses may lead to val
