905984-03-4

Upstream product

• 875545-07-6 (S)-[1-Methoxy-1-(1-phenylethoxy)methylvinyloxy]triethylsilane 
• 209852-87-9 (-)-(1'S,2S)-2α-(1-Phenylethoxy)-8-oxabicyclo[3.2.1]oct-6-en-3-one 
• 403666-51-3 (1'S,1R,2S,5S)-2-(1'-phenylethoxy)-3-triethylsilanyloxy-8-oxabicyclo[3.2.1]octa-3,6-diene 

Downstream Products

• 905984-04-5 (1S,2S,4S,5R)-2-fluoro-4-acetoxy-8-oxabicyclo[3.2.1]oct-6-en-3-one 

Relevant academic research and scientific papers

Bicyclo[3.2.1]octanone catalysts for asymmetric alkene epoxidation: the effect of disubstitution

A series of 2-fluoro-8-oxabicyclo[3.2.1]octan-3-ones are prepared and tested as catalysts for alkene epoxidation with Oxone. These catalysts provide trans-stilbene oxide with up to 83% ee, but the highest ee value is obtained with the monofluorinated ketone 2: both 2,2- and 2,4-disubstituted catalysts afford epoxide of lower ee.