906075-26-1

Basic information

• Product Name: 1-aminocycloheptanecarboxamide(SALTDATA: FREE)
• Synonyms: 1-aminocycloheptanecarboxamide(SALTDATA: FREE);1-Aminocycloheptane-1-carboxamide
• CAS NO: 906075-26-1
• Molecular Formula: C₈H₁₆N₂O
• Molecular Weight: 156.22544
• Mol File: 906075-26-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-aminocycloheptanecarboxamide(SALTDATA: FREE)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-aminocycloheptanecarboxamide(SALTDATA: FREE)(906075-26-1)
• EPA Substance Registry System: 1-aminocycloheptanecarboxamide(SALTDATA: FREE)(906075-26-1)

Safety Data

• Hazardous Substances Data: 906075-26-1(Hazardous Substances Data)

Usage

Class

Carboxamides

Appearance

White to off-white crystalline powder

Solubility

Soluble in water and organic solvents

Applications

a. Intermediate in the synthesis of pharmaceutical drugs
b. Reagent in organic chemistry reactions

Hazardous classification

Classified as a hazardous substance

Handling and storage

Requires careful management to avoid potential health and environmental risks

Upstream product

• 502-42-1 cycloheptanone 
• 123193-99-7 1-aminocycloheptanecarbonitrile 

Relevant articles and documents

Design and synthesis of certain substituted cycloalkanecarboxamides structurally related to safinamide with anticonvulsant potential

A series of novel safinamide derivatives were synthesized and biologically evaluated for their anticonvulsant activity against maximal electroshock seizure assay and subcutaneous pentylenetetrazole (s.c. PTZ) screening test. Compound 13b is the most active derivative in s.c. PTZ screening test with an ED50 value lower than that of safinamide by about tenfold. A molecular modeling study, including fitting to sodium channel blockers 3D-pharmacophore model and docking into a branched-chain aminotransferase enzyme active site were consistent with the in vivo results.