906366-48-1

Basic information

• Product Name: (2R,3R)-2-[N-(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propanoic acid
• Synonyms: (2R,3R)-2-[N-(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propanoic acid
• CAS NO: 906366-48-1
• Molecular Weight: 337.116
• Mol File: 906366-48-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R)-2-[N-(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-2-[N-(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propanoic acid(906366-48-1)
• EPA Substance Registry System: (2R,3R)-2-[N-(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propanoic acid(906366-48-1)

Safety Data

• Hazardous Substances Data: 906366-48-1(Hazardous Substances Data)

Upstream product

• 5872-74-2 (2RS,3RS)-2-amino-3-hydroxy-3-(4-nitro-phenyl)-propionic acid 
• 7384-89-6 chloramphenicol 

Relevant articles and documents

Oxidation of amino diols mediated by homogeneous and heterogeneous TEMPO

The conversion of amino diols to aminohydroxy acids by oxidation of the primary hydroxy group mediated by homogeneous and heterogeneous TEMPO (2,2,6,6-tetramethylpiperidine 1-oxyl radical) is reported. The synthesis uses NaOCl as primary oxidant and TEMPO, either dissolved in the homogeneous phase or entrapped in a sol-gel matrix, as catalytic mediator. Homogeneous TEMPO is suitable for the oxidation of aliphatic methylamino diols, while the hybrid organic-inorganic silica sol-gel catalysts are more selective mediators for the oxidation of benzylic amino diols like the potent antibiotic chloramphenicol which, under homogeneous conditions, are unselectively oxidized to benzoic acids.