906370-94-3Relevant academic research and scientific papers
Asymmetric epoxidation, Michael addition, and triple cascade reaction using polymer-supported prolinol-based auxiliaries
Varela, Michael C.,Dixon, Seth M.,Lam, Kit S.,Schore, Neil E.
, p. 10087 - 10090 (2008)
The applicability of polymer-supported diphenylprolinol derivatives in directing either asymmetric epoxidation or Michael addition of suitable α,β-unsaturated substrates has been assessed. Epoxidation of cinnamaldehyde in the solid state give poorer yield
Novel Functional Hollow and Multihollow Organic Microspheres: Enhanced Efficiency in a Complex, Heterogeneous, Asymmetric, Three-Component/Triple Organocascade Reaction
Dai, Fuqiang,Zhao, Zhiwei,Xie, Guangxin,Feng, Dandan,Ma, Xuebing
, p. 89 - 93 (2017/01/17)
The pioneered construction of monodisperse hollow and multihollow J?rgensen–Hayashi-functionalized microspheres with a well-defined spherical morphology, high surface area, and large pore volume were developed by initial dispersion copolymerization of the J?rgensen–Hayashi organocatalyst with acrylamide and styrene monomers cross-linked by p-divinylbenzene and ethylene glycol dimethacrylate, respectively, on the surface of poly(styrene/acrylic acid) (PS) microspheres to form core–shell structures, followed by removal of the PS core by etching in organic solvents. The as-prepared hollow and multihollow microspheres were able to achieve better mass transfer in a complex heterogeneous asymmetric three-component/triple cascade reaction and provided the products in good yields (31–61 %) with excellent stereoselectivities (80:20–93:7 dr, >99 % ee).
Asymmetric triple cascade organocatalytic reaction in water: Construction of polyfunctional cyclohexene building blocks having multiple stereocenters
Jia, Yaomei,Mao, Zhifeng,Wang, Rui
experimental part, p. 2018 - 2023 (2012/03/22)
An asymmetric triple cascade organocatalytic reaction was carried out in water, which led to the construction of polyfunctional cyclohexene building blocks with multiple stereocenters with good diastereoselectivity and excellent enantioselectivity. This a
Asymmetric synthesis of polyfunctionalized mono-, Bi-, and tricyclic carbon frameworks via organocatalytic domino reactions
Enders, Dieter,Huettl, Matthias R. M.,Raabe, Gerhard,Bats, Jan W.
experimental part, p. 267 - 279 (2009/04/08)
An asymmetric organocatalytic multi-component domino reaction is used as a key process for the stereoselective synthesis of polysubstituted mono- and bicyclic cyclohexene-carbaldehydes. Furthermore, the extension of the domino reaction and further synthetic transformations of the cascade products were investigated. The combination of the three-step cascade with an intramolecular Diels-Alder reaction opens up an entry to tricyclic decahydroacenaphthylene and decahydrophenalene skeletons, which are valuable characteristic carbon cores of natural products.
