90641-64-8

Upstream product

• 6629-60-3 ethylhydrazine oxalic acid salt 
• 94-05-3 ethyl (ethoxymethylene)cyanoacetate 
• 74-96-4 ethyl bromide 
• 6994-25-8 3-amino-4-pyrazolecarboxylic acid ethyl ester 

Downstream Products

• 79291-40-0 Ethyl 1-ethyl-3-(4-fluoro-2-nitroanilino)pyrazole-4-carboxylate 
• 1361961-20-7 ethyl 5-(3-benzoylthioureido)-1-ethyl-1H-pyrazole-4-carboxylate 
• 1361961-21-8 ethyl 3-(3-benzoylthioureido)-1-ethyl-1H-pyrazole-4-carboxylate 
• 79291-70-6 ethyl 3-(2-amino-4-fluoroanilino)-1-ethylpyrazole-4-carboxylate 
• 166332-64-5 6-ethyl-2-(4-bromophenyl)amino-3-aminopyrazolo<3,4-d>pyrimidin-4-one 
• 166332-63-4 1-ethyl-N-(4-carboethoxypyrazol-3-yl)-N'-(4-bromophenyl)thiourea 

Relevant academic research and scientific papers

COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS

The present invention relates to pharmaceutical agents administered to a subject either in combination or in series for the treatment of a Respiratory Syncytial Virus (RSV) infection, wherein treatment comprises administering a compound effective to inhibit the function of the RSV and an additional compound or combinations of compounds having anti-RSV activity.

BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS

The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Respiratory Syncytial Virus (RSV). The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from RSV infection. The invention also relates to methods of treating an RSV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

AZOLOPYRIDINE AND AZOLOPYRIMIDINE COMPOUNDS AND METHODS OF USE THEREOF

Provided herein are azolopyridine and azolopyrimidine compounds for treatment of JAK kinase mediated diseases, including JAK2 kinase-, JAK3 kinase- or TYK2 kinase-mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions.