906459-23-2Relevant academic research and scientific papers
Effect of substitution on novel tricyclic HIV-1 integrase inhibitors
Fardis, Maria,Jin, Haolun,Jabri, Salman,Cai, Ruby Z.,Mish, Michael,Tsiang, Manuel,Kim, Choung U.
, p. 4031 - 4035 (2007/10/03)
A series of novel tricyclic inhibitors of HIV-1 integrase enzyme was prepared. The effect of substitution at C-6 of the 9-hydroxy-6,7-dihydropyrrolo[3,4-g]quinolin-8-one compounds was studied in vitro. Inhibitors with small side chains at C-6 were general
