906543-03-1

Basic information

• Product Name: (5-Fluoro-1-methyl-1H-indol-2-yl)methanol
• Synonyms: (5-Fluoro-1-methyl-1H-indol-2-yl)methanol
• CAS NO: 906543-03-1
• Molecular Formula: C₁₀H₁₀FNO
• Molecular Weight: 179.1909032
• Mol File: 906543-03-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (5-Fluoro-1-methyl-1H-indol-2-yl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (5-Fluoro-1-methyl-1H-indol-2-yl)methanol(906543-03-1)
• EPA Substance Registry System: (5-Fluoro-1-methyl-1H-indol-2-yl)methanol(906543-03-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 906543-03-1(Hazardous Substances Data)

Usage

General Description

(5-Fluoro-1-methyl-1H-indol-2-yl)methanol is a chemical compound with the molecular formula C10H10FNO. It is an indole derivative with a fluorine and methyl group attached to the indole ring. (5-Fluoro-1-methyl-1H-indol-2-yl)methanol is used in research and pharmaceutical development as a building block for the synthesis of various indole-based compounds with potential biological activities. Its structure and properties make it a valuable intermediate for the development of new drugs and agrochemicals. Additionally, it may also be used as a reference standard in analytical chemistry for the identification and quantification of similar compounds.

Upstream product

• 108797-28-0 ethyl 5-fluoro-1-methyl-1H-indole-2-carboxylate 
• 893731-88-9 5-fluoro-1-methyl-1H-indole-2-carboxylic acid methyl ester 
• 167631-84-7 5-fluoro-1H-indole-2-carboxylic acid methyl ester 

Downstream Products

• 883531-48-4 5-fluoro-1-methyl-1H-indole-2-carbaldehyde 
• 1434621-38-1 6-fluoro-9-methyl-4-phenyl-2-tosyl-1,2,3,4-tetrahydro-β-carboline 

Relevant articles and documents

VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL INHIBITOR

A compound represented by the following General Formula (I), a tautomer or a stereoisomer of the compound, a pharmaceutically acceptable salt thereof, or a solvate thereof, is used as a voltage-dependent T-type calcium channel blocker: wherein A represents a fused ring which may have a substituent, the fused ring being composed of a 5-membered heteroaryl group or a 5-membered or 6-membered heterocyclic ring and a benzene ring or the like, the 5-membered heteroaryl group having one to three identical or different heteroatoms as a ring-constituting element(s) having at least one substituent such as an alkoxy group having 1 to 8 carbon atoms and substituted with 1 to 5 halogen atoms; R represents a hydrogen atom or the like; B represents CR5(Q1) or NQ2, herein Q1 represents a benzimidazole group which may have a substituent; Q2 represents an alkyl group having 1 to 8 carbon atoms which may have a substituent, a heteroaryl group which may have a substituent, or the like; R0, R1, R2, R3, R4, and R5 each represent a hydrogen atom or the like; and n and m each represent 0, 1, or 2, provide that n and m are not 0 and 2 at the same time.

New indole-isoxazolone derivatives: Synthesis, characterisation and in vitro SIRT1 inhibition studies

A new series of indole-isoxazolone hybrids bearing substituted amide, substituted [(1,2,3-triazol-4-yl)methoxy]methyl group or substituted benzylic ether at position-2 of the indole nucleus was synthesised using a facile synthetic route and the molecules

Platinum-catalyzed intramolecular asymmetric hydroarylation of unactivated alkenes with indoles

A 1:1 mixture of the platinum bis(phosphine) complex [(S)-4]PtCl 2 [(S)-4 = (S)-3,5-t-Bu-4-MeO-MeOBIPHEP] catalyzes the intramolecular asymmetric hydroarylation of 2-(4-pentenyl)indoles in moderate to good yield with up to 90% ee.