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906556-66-9

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906556-66-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 906556-66-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,6,5,5 and 6 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 906556-66:
(8*9)+(7*0)+(6*6)+(5*5)+(4*5)+(3*6)+(2*6)+(1*6)=189
189 % 10 = 9
So 906556-66-9 is a valid CAS Registry Number.

906556-66-9Downstream Products

906556-66-9Relevant articles and documents

II. SAR studies of pyridyl-piperazinyl-piperidine derivatives as CXCR3 chemokine antagonists

Shao, Yuefei,Anilkumar, Gopinadhan N.,Carroll, Carolyn Diianni,Dong, Guizhen,Hall III, James W.,Hobbs, Doug W.,Jiang, Yueheng,Jenh, Chung-Her,Kim, Seong Heon,Kozlowski, Joseph A.,McGuinness, Brian F.,Rosenblum, Stuart B.,Schulman, Inna,Shih, Neng-Yang,Shu, Youheng,Wong, Michael K.C.,Yu, Wensheng,Zawacki, Lisa Guise,Zeng, Qingbei

, p. 1527 - 1531 (2011/04/16)

The structure-human CXCR3 binding affinity relationship of a series of pyridyl-piperazinyl-piperidine derivatives was explored. The optimization campaign highlighted the pronounced effect of 2'-piperazine substitution on CXCR3 receptor affinity. Analog 18j, harboring a 2'(S)-ethylpiperazine moiety, exhibited a human CXCR3 IC50 of 0.2 nM.

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