169447-70-5

Basic information

• Product Name: (S)-1-N-Boc-2-methylpiperazine
• Synonyms: (R)-2-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;(R)-2-METHYL-1-BOC-PIPERAZINE;(S)-TERT-BUTYL 2-METHYLPIPERAZINE-1-CARBOXYLATE;(S)-1-N-BOC-2-METHYL PIPERAZINE;(S)-2-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;(R)-TERT-BUTYL 2-METHYLPIPERAZINE-1-CARBOXYLATE;(S)-1-Boc-2-methyl-piperazine;Tert-Butyl2(S)-methylpiperazine-1-carboxylate
• CAS NO: 169447-70-5
• Molecular Formula: C₁₀H₂₀N₂O₂
• Molecular Weight: 200.28
• Product Categories: pharmacetical;Piperaizine;Chiral Reagents;Heterocycles
• Mol File: 169447-70-5.mol
• Article Data: 10

Chemical Properties

• Melting Point: 43.0 to 47.0 °C
• Boiling Point: 268.74 °C at 760 mmHg
• Flash Point: 116.33 °C
• Appearance: /
• Density: 0.998 g/cm³
• Vapor Pressure: 0.008mmHg at 25°C
• Refractive Index: 1.459
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: 8.49±0.40(Predicted)
• CAS DataBase Reference: (S)-1-N-Boc-2-methylpiperazine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-N-Boc-2-methylpiperazine(169447-70-5)
• EPA Substance Registry System: (S)-1-N-Boc-2-methylpiperazine(169447-70-5)

Safety Data

• RIDADR: UN3077
• Hazardous Substances Data: 169447-70-5(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 169447-70-5 differently. You can refer to the following data:
1. (S)-1-N-Boc-2-methylpiperazine is used in the preparation of pyrazolo[3,4-b]pyridine dual pharmacophores as PDE4-muscarinic antagonists.
2. Used in the preparation of pyrazolo[3,4-b]pyridine dual pharmacophores as PDE4-muscarinic antagonists.

InChI:InChI=1/C10H20N2O2/c1-8-7-11-5-6-12(8)9(13)14-10(2,3)4/h8,11H,5-7H2,1-4H3/t8-/m1/s1

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 74879-18-8 (S)-2-methylpiperazine 
• 888973-02-2 (2S)-1-piperazinecarboxylic acid, 2-methyl-4-(triphenylmethyl)-1,1-dimethylethyl ester 
• 859517-91-2 C₁₈H₂₆N₂O₄ 
• 170033-54-2 (S)-<2-<(2-Hydroxyethyl)(phenylmethyl)amino>-1-methyl-2-oxoethyl>carbamic acid 1,1-dimethylethyl ester 
• 170033-57-5 (S)-3-Methyl-1-(phenylmethyl)piperazin-2-one 
• 132871-10-4 (3S)-1-benzyl-3-methylpiperazine-2,5-dione 
• 132871-12-6 (S)-3-Methyl-1-(phenylmethyl)piperazine 
• 118375-95-4 methyl (S)-2-(2-chloroacetamido)propanoate 
• 169447-69-2 tert-Butyl (S)-2-methyl-4-(phenylmethyl)-1-piperazinecarboxylate 

Downstream Products

• 923565-72-4 1,1-dimethylethyl (2S)-2-methyl-4-((4-(2-(methyloxy)-2-oxoethyl)phenyl)methyl)-1-piperazinecarboxylate 
• 923565-73-5 (4-(((3S)-4-(((1,1-dimethylethyl)oxy)carbonyl)-3-methyl-1-piperazinyl)methyl)phenyl)acetic acid 
• 1204926-01-1 C₁₇H₂₃F₃N₂O₄S 
• 1204535-18-1 1,1-dimethylethyl (2S)-4-[(4-bromo-2-methylphenyl)sulfonyl]-2-methyl-1-piperazinecarboxylate 
• 1204535-31-8 1,1-dimethylethyl (2S)-4-{[2-bromo-4-(trifluoromethyl)phenyl]sulfonyl}-2-methyl-1-piperazinecarboxylate 
• 1272972-70-9 tert-butyl (2S)-2-methyl-4-(5-{[4-(methylsulfonyl)benzyl]oxy}pyrimidin-2-yl)piperazine-1-carboxylate 
• 1460030-95-8 2,5-dioxopyrrolidin-1-yl (2S)-4-{[2-fluoro-4-(morpholin-4-yl)phenyl]methyl}-2-methylpiperazine-1-carboxylate 
• 1460031-02-0 2,5-dioxopyrrolidin-1-yl (2S)-4-{[2-chloro-4-(morpholin-4-yl)phenyl]methyl}-2-methylpiperazine-1-carboxylate 

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