90656-49-8Relevant articles and documents
Metal catalyst-free amination of 2-chloro-5-nitrobenzoic acid in superheated water
Lan, Cong,Xia, Zhi-Ning,Li, Zheng-Hua,Liang, Rong-Hui
, p. 726 - 728 (2013/02/23)
A series of N-arylanthranilic acid derivatives were synthesised by amination of 2-chloro-5-nitrobenzoic acid with various arylamine in superheated water with potassium carbonate as base. Good yields were achieved within 2-3 h at 150-190 °C. The results indicated that this metal catalyst-free method is a simple, environmentally-friendly and efficient synthesis of N-phenylanthranilic acid derivatives. Furthermore, it will work with an alkylamine and phenol.
Catalyst-free microwave-assisted amination of 2-chloro-5-nitrobenzoic acid
Baqi, Younis,Mueller, Christa E.
, p. 5908 - 5911 (2008/02/10)
(Chemical Equation Presented) The synthesis of N-substituted 5-nitroanthranilic acid derivatives 3a-w was achieved by a new, mild, microwave-assisted, regioselective amination reaction of 5-nitro-2-chlorobenzoic acid (1a) with a diverse range of aliphatic