90657-55-9

Basic information

• Product Name: trans-4-Cyclohexyl-L-proline hydrochloride
• Synonyms: TRANS-4-CYCLOHEXYL-L-PROLINE HYDROCHLORIDE;TRANS-4-CYCLOHEXYL-L-PROLINE MONOHYDRO-CHLORIDE;trans-4-Cyclohexyl-L-Proline HCl;Trans-4-Cyclohexyl-P-prolinehydrochloride;trans-4-Cyclohexyl proline HCl;TRANS-4-CYCLOHEXYL-L-PROLINE MONOHYDRO-CHLORIDE(FOSINOPRIL INTERMEDIATE );(4S)-4-Cyclohexyl-L-proline Hydrochloride;Trans-4-Cyclohexyl-L-proline hydrochloride (for Fosinopril)
• CAS NO: 90657-55-9
• Molecular Formula: C₁₁H₁₉NO₂*ClH
• Molecular Weight: 233.74
• EINECS: 419-160-1
• Product Categories: INTERMEDIATESOFFOSINOPRIL;(intermediate of fosinopril);Chiral Reagents;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 90657-55-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 257-267°C
• Appearance: white solid
• Storage Temp.: Hygroscopic, Refrigerator, Under Inert Atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: trans-4-Cyclohexyl-L-proline hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: trans-4-Cyclohexyl-L-proline hydrochloride(90657-55-9)
• EPA Substance Registry System: trans-4-Cyclohexyl-L-proline hydrochloride(90657-55-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22-38-41-43-62
• Safety Statements: 22-26-36/37/39
• Hazardous Substances Data: 90657-55-9(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

It is an intermediate for the synthesis of angiotensin-converting enzyme inhibitors, e.g. Fosinopril (F727800).

InChI:InChI=1/C11H19NO2.ClH/c13-11(14)10-6-9(7-12-10)8-4-2-1-3-5-8;/h8-10,12H,1-7H2,(H,13,14);1H/t9?,10-;/m0./s1

Upstream product

• 90657-53-7 trans-4-Phenyl-L-proline hydrochloride 
• 9065-68-3 1,3-Benzenedicarboxylic acid, polymer with 2,5-furandione, oxybispropanol and 1,2-propanediol 
• 90656-45-4 4-chloro-2-[(4-chlorophenyl)amino]benzoic acid 
• 9065-63-8 PPG-10-BUTETH-9 
• 906560-16-5 5-(NAPHTHALEN-1-YL)FURAN-2(3H)-ONE 
• 906559-60-2 (2S,5R)-2-ETHYL-5-METHYL-N-BOC-PIPERAZINE 
• 906559-46-4 Methyl 4-(4-Boc-1-piperazinyl)-3-chlorobenzoate 
• 906559-32-8 tert-Butyl 4-[3-bromo-5-(methoxycarbonyl)pyridin-2-yl]piperazine-1-carboxylate 
• 906557-98-0 1-METHOXY-2,5-DIIODOBENZENE 
• 906552-20-3 Atorvastatin LactaM Phenanthrene Methyl Ester (Mixture of DiastereoMers) 
• 906552-19-0 Atorvastatin pyrrolidone lactone 
• 906552-18-9 Atorvastatin Lactam Impurity 
• 906548-54-7 N-[[2-chloro-3-(trifluoromethyl)phenyl]methyleneamino]-4-hydroxy-benzamide 
• 906543-03-1 (5-Fluoro-1-methyl-1H-indol-2-yl)methanol 

Downstream Products

• 90657-90-2 5-(3-chlorophenyl)-4-cyclohexyl-2,4-dihydro-3H-1,2,4-triazole-3-thione 
• 9065-82-1 Formaldehyde, polymer with dimethylphenol and methylphenol 
• 9065-96-7 Fibrinase 
• 90660-09-6 (t-ButyldiMethylsilyloxy)cyclopropanecarbaldehyde 
• 90660-20-1 4,4-difluororetinoic acid 
• 90660-21-2 4,4-difluororetinol 
• 90660-22-3 4,4-difluororetinyl acetate 
• 90660-23-4 (9cis,13cis)-4,4-difluoro-O~15~-hexadecanoylretinol 
• 90660-79-0 (5Z)-3-[2-(1H-benzimidazol-2-yl)phenyl]-2-methyl-5-(phenylmethylidene)-3,5-dihydro-4H-imidazol-4-one 
• 90660-80-3 (5Z)-3-[2-(1H-benzimidazol-2-yl)phenyl]-5-[(4-methoxyphenyl)methylidene]-2-methyl-3,5-dihydro-4H-imidazol-4-one 
• 90660-81-4 (5Z)-3-[2-(1H-benzimidazol-2-yl)phenyl]-5-[(3,4-dimethoxyphenyl)methylidene]-2-methyl-3,5-dihydro-4H-imidazol-4-one 
• 90660-82-5 (5Z)-3-[3-(1H-benzimidazol-2-yl)phenyl]-2-methyl-5-(phenylmethylidene)-3,5-dihydro-4H-imidazol-4-one 
• 90660-83-6 (5Z)-3-[3-(1H-benzimidazol-2-yl)phenyl]-5-[(4-methoxyphenyl)methylidene]-2-methyl-3,5-dihydro-4H-imidazol-4-one 
• 90660-84-7 (5Z)-3-[3-(1H-benzimidazol-2-yl)phenyl]-5-[(3,4-dimethoxyphenyl)methylidene]-2-methyl-3,5-dihydro-4H-imidazol-4-one 

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