90664-10-1

Upstream product

• 90664-09-8 (1E,3S,4R)-(-)-4-Methyl-5--1-phenyl-1-penten-3-ol 
• 74-88-4 methyl iodide 
• 90545-69-0 (1R,2S)-1-(furan-2-yl)-2-methylpropane-1,3-diol 
• 85199-60-6 (R-(R^*,R^*))-β-hydroxy-α-methyl-2-furanpropanoate 
• 1449-46-3 benzyltriphenylphosphonium bromide 
• 70633-78-2 (3R,4E)-(-)-3-Hydroxy-5-phenyl-4-pentensaeure-methylester 
• 90695-51-5 (2R,3S,4E)-(-)-2-Methyl-5-phenyl-4-penten-1,3-diol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 90695-53-7 (2S,3S,4E)-(-)-3-Hydroxy-2-methyl-5-phenyl-4-pentensaeure-methylester 

Downstream Products

• 90664-12-3 (2R,3S,4E)-(-)-(3-Methoxy-2-methyl-5-phenyl-4-pentenyl)-p-toluolsulfonat 
• 73341-71-6 (2Z,3R,4S,5E)-(+)-4-Methoxy-2-(methoxymethylen)-3-methyl-6-phenyl-5-hexensaeure-methylester 
• 90695-50-4 (2E,3R,4S,5E)-methyl 4-methoxy-2-(methoxymethylene)-3-methyl-6-phenylhex-5-enoate 
• 90695-52-6 (3R,4R,5E)-(+)-4-Methoxy-3-methyl-6-phenyl-5-hexensaeure-methylester 
• 90664-13-4 (3R,4R,5E)-(+)-4-Methoxy-3-methyl-6-phenyl-5-hexennitril 

Relevant academic research and scientific papers

THE USE OF A VERSATILE BUILDING BLOCK HAVING TWO CHIRAL CENTERS A TOTAL SYNTHESIS OF (-)-OUDEMANSIN

(-)-Oudemansin (4) has been synthesized from the chiral synthon 2 obtained by microbiological asymmetric reduction of the prochiral β-keto ester 1.Keywords - total synthesis; antibiotic; cleavage of furan; α-methyl β-hydroxy ester

Syntheses of (+)-Oudemansin and (+)-Epioudemansin Starting from Enantiomerically Pure Precursors; Absolute Configuration of the Naturally Occuring (-)-Oudemansin

The syntheses of the four optically pure methyl (E)-3-hydroxy-2-methyl-5-phenyl-4-pentenoates (+)- and (-)-5 as well as (+)- and (-)-6 were achieved by consecutive methylation and protonation of enolates, starting from (+)- and (-)-4.The esters (+)-6 and