90672-05-2

Upstream product

• 693-92-5 3-methylisothiazole 
• 122-03-2 (4-isopropylbenzaldehyde) 

Downstream Products

• 90695-86-6 4-(1-methylethyl)phenyl 3-methylisothiazol-5-yl ketone 
• 90671-49-1 {4-[(4-Isopropyl-phenyl)-(3-methyl-isothiazol-5-yl)-methyl]-piperazin-1-yl}-phenyl-methanone 
• 90671-47-9 1-[(4-Isopropyl-phenyl)-(3-methyl-isothiazol-5-yl)-methyl]-4-methanesulfonyl-piperazine 
• 90671-45-7 4-[(4-Isopropyl-phenyl)-(3-methyl-isothiazol-5-yl)-methyl]-piperazine-1-carboxylic acid ethyl ester 
• 90671-43-5 2-{4-[(4-Isopropyl-phenyl)-(3-methyl-isothiazol-5-yl)-methyl]-piperazin-1-yl}-ethanol 
• 90672-32-5 1-[(4-Isopropyl-phenyl)-(3-methyl-isothiazol-5-yl)-methyl]-3,5-dimethyl-piperazine 
• 90672-38-1 (4-Isopropyl-phenyl)-(3-methyl-isothiazol-5-yl)-(1-methyl-piperidin-4-yl)-methanol 
• 90672-26-7 4-[(4-Isopropyl-phenyl)-(3-methyl-isothiazol-5-yl)-methyl]-morpholine 
• 90671-41-3 1-[(4-Isopropyl-phenyl)-(3-methyl-isothiazol-5-yl)-methyl]-piperazine 
• 90670-95-4 1-[(4-Isopropyl-phenyl)-(3-methyl-isothiazol-5-yl)-methyl]-4-methyl-piperazine 
• 90672-29-0 1-[(4-Isopropyl-phenyl)-(3-methyl-isothiazol-5-yl)-methyl]-piperidine 
• 90672-36-9 {2-[(4-Isopropyl-phenyl)-(3-methyl-isothiazol-5-yl)-methylsulfanyl]-ethyl}-dimethyl-amine 
• 90672-43-8 5-[(4-Isopropyl-phenyl)-(2-pyrrolidin-1-yl-ethoxy)-methyl]-3-methyl-isothiazole 
• 90672-31-4 [(4-Isopropyl-phenyl)-(3-methyl-isothiazol-5-yl)-methyl]-pyridin-3-yl-amine 

Relevant academic research and scientific papers

Heterocyclic Analogues of Chlorcyclizine with Potent Hypolipidemic Activity

A series of piperazines was synthesized and their effect of reducing serum cholesterol and triglyceride levels in the rat was evaluated.A systematic exploration of the structure-activity relationships led to the synthesis of (R,S)-(3,5-dimethylisoxazol-4-yl)(4-methylpiperazin-1-yl)methane dihydrochloride (M and B 31426), which had potent activity in lowering serum lipid levels at a daily oral dose of 2 mg/kg and was 100 times more potent than clofibrate.