906758-53-0Relevant academic research and scientific papers
Elemental Sulfur-Promoted Oxidative Rearranging Coupling between o-Aminophenols and Ketones: A Synthesis of 2-Alkyl benzoxazoles under Mild Conditions
Nguyen, Thanh Binh,Retailleau, Pascal
, p. 3887 - 3890 (2017)
In the presence of N-methylpiperidine, elemental sulfur was found to act as excellent oxidant in promoting oxidative rearranging coupling between o-aminophenols and ketones. A wide range of 2-alkylbenzoxazoles was obtained under mild conditions.
N-heterocyclic carbene-Pd(II)-1-methylimidazole complex catalyzed C-H bond benzylation of (benzo)oxazoles with benzyl chlorides
Ji, Ya-Yun,Zhang, Yu,Hu, Yuan-Yuan,Shao, Li-Xiong
, p. 6818 - 6823 (2015/08/24)
The first example of phosphine-free, NHC-Pd(II) complex catalyzed direct C-H bond benzylation of (benzo)oxazoles with benzyl chlorides was reported in this paper. Under the suitable conditions, all reactions worked well enough to give the desired C2-benzylated products in good to almost quantitative yields, providing a facile and straight pathway for the C-H bond benzylation of (benzo)oxazoles within short time.
Palladium-catalyzed decarboxylative couplings of 2-(2-Azaaryl)acetates with aryl halides and triflates
Shang, Rui,Yang, Zhi-Wei,Wang, Yan,Zhang, Song-Lin,Liu, Lei
supporting information; experimental part, p. 14391 - 14393 (2010/12/19)
Pd-catalyzed decarboxylative cross-couplings of 2-(2-azaaryl)acetates with aryl halides and triflates have been discovered. This reaction is potentially useful for the synthesis of some functionalized pyridines, quinolines, pyrazines, benzoxazoles, and benzothiazoles. Theoretical analysis shows that the nitrogen atom at the 2-position of the heteroaromatics directly coordinates to Pd(II) in the decarboxylation transition state.
