90679-70-2Relevant academic research and scientific papers
STUDIES ON SRN1 REACTIONS - 9 A NEW ACCESS TO THE ISOQUINOLINE RING SYSTEM
Beugelmans, Rene,Chastanet, Jacqueline,Roussi, Georges
, p. 311 - 314 (2007/10/02)
The SRN1 reaction between o-halogeno-benzylamines and enolates derived from a series of ketones and aldehydes affords 1, 2 dihydro-isoquinolines from which are obtained (i) the isoquinoline derivatives, either spontaneously or by treatment on Pd-C and (ii) the 1, 2, 3, 4 tetrahydro-isoquinoline derivatives after sodium borohydride reduction.
