906794-95-4

Basic information

• Product Name: 1-[4-(tert-butyl-diphenyl-silanyloxy)-5-trityloxymethyl-tetrahydro-furan-2-yl]-5-iodo-1H-pyrimidine-2,4-dione
• Synonyms: 1-[4-(tert-butyl-diphenyl-silanyloxy)-5-trityloxymethyl-tetrahydro-furan-2-yl]-5-iodo-1H-pyrimidine-2,4-dione
• CAS NO: 906794-95-4
• Molecular Weight: 834.826
• Mol File: 906794-95-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[4-(tert-butyl-diphenyl-silanyloxy)-5-trityloxymethyl-tetrahydro-furan-2-yl]-5-iodo-1H-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(tert-butyl-diphenyl-silanyloxy)-5-trityloxymethyl-tetrahydro-furan-2-yl]-5-iodo-1H-pyrimidine-2,4-dione(906794-95-4)
• EPA Substance Registry System: 1-[4-(tert-butyl-diphenyl-silanyloxy)-5-trityloxymethyl-tetrahydro-furan-2-yl]-5-iodo-1H-pyrimidine-2,4-dione(906794-95-4)

Safety Data

• Hazardous Substances Data: 906794-95-4(Hazardous Substances Data)

Upstream product

• 15414-61-6 2'-deoxy-5-iodo-5'-O-(triphenylmethyl)uridine 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 910040-51-6 1-[4-(tert-butyl-diphenyl-silanyloxy)-5-trityloxymethyl-tetrahydro-furan-2-yl]-5-trimethylsilanylethynyl-1H-pyrimidine-2,4-dione 
• 906794-96-5 1-[4-(tert-butyl-diphenyl-silanyloxy)-5-trityloxymethyl-tetrahydro-furan-2-yl]-5-ethynyl-1H-pyrimidine-2,4-dione 
• 906794-97-6 5-ethynyl-3'-O-TBDPS-2'-deoxyuridine 

Relevant articles and documents

Synthesis of 5-ethynyl-2′-deoxyuridine-5′-boranomono phosphate as a potential thymidylate synthase inhibitor

The 5-ethynyl-2′-deoxyuridine nucleoside and the 5′- boranomonophosphate nucleotide were synthesized as analogs of 5-fluoro-2′-deoxyuridine monophosphate (5-FdUMP), a widely used mechanism-based inhibitor of thymidylate synthase. Synthesis was carried out