910040-51-6Relevant articles and documents
Synthesis of 5-ethynyl-2′-deoxyuridine-5′-boranomono phosphate as a potential thymidylate synthase inhibitor
Khan, Shoeb I.,Dobrikov, Mikhail I.,Shaw, Barbara Ramsay
, p. 1047 - 1049 (2007/10/03)
The 5-ethynyl-2′-deoxyuridine nucleoside and the 5′- boranomonophosphate nucleotide were synthesized as analogs of 5-fluoro-2′-deoxyuridine monophosphate (5-FdUMP), a widely used mechanism-based inhibitor of thymidylate synthase. Synthesis was carried out