90702-95-7Relevant academic research and scientific papers
An enantiomeric pair of steroidal neuromuscular blockers
Marshall,McIndewar,Peters,et al.
, p. 43 - 47 (2007/10/02)
The synthesis is described of the bis-quaternary ammonium compound 17a-methyl-3β-(N-pyrrolidinyl)-17a-aza-D-homo-5-estrene bis(methiodide) and its enantiomer. In the cat both possess marked non-depolarizing neuromuscular blocking activity of short duration and rapid onset. A side effect is vagolytic activity. Both enantiomers are about equipotent.
