90712-80-4Relevant academic research and scientific papers
Photocatalytic initiation of thiol-ene reactions: Synthesis of thiomorpholin-3-ones
Keylor, Mitchell H.,Park, James E.,Wallentin, Carl-Johan,Stephenson, Corey R.J.
, p. 4264 - 4269 (2014/06/09)
A mild, redox neutral photocatalytic method for alkene hydrothiolation is reported. Utilizing visible-light activation, catalytic radical initiation is achieved with the transition metal complex Ru(bpy)3Cl2, enabling rapid access to a diverse set of thiol-ene coupled products in excellent yield. On the basis of a strong observed background reaction in some cases, we have developed a solvent-free, Lewis acid-promoted tandem amidation-hydrothiolation sequence, providing thiomorpholin-3-ones in a one-pot operation from commercially available materials.
New synthesis of tetrahydro-1,4-thiazine-3-ones from 1,2- aminopropanethiols and α-chlorocarboxylic acids
Magerramov,Allakhverdiev,Akhmedova,Caple,Zhdankin
, p. 721 - 728 (2007/10/03)
Tetrahydro-1,4-thiazine-3-ones 5 can be efficiently prepared by the condensation of 1,2-aminopropanethiols 1 and sodium chlorocarboxylates 4 under basic conditions.
REACTION OF AMINO THIOLS WITH CHLOROACETIC ACID AND ITS ESTERS
Allakhverdiev, M. A.,Farzaliev, V. M.,Khoiskaya, T. M.,Ibragimov, N. Yu.,Cherkasova, E. M.
, p. 261 - 263 (2007/10/02)
The reaction of amino thiols with chloroacetic acid esters leads to the formation of amino mercapto esters, whereas 6-alkyl(alkoxy)-N-aryltetrahydro-1,4-thiazine-3-ones are formed in the reaction with chloroacetic acid.
