90731-99-0 Usage
Description
3-Chloro-4-isopropylpyridine, a pyridine derivative with the molecular formula C8H10ClN, features a chlorine atom at the 3rd position and an isopropyl group at the 4th position. This chemical compound serves as a versatile intermediate in the synthesis of a variety of pharmaceuticals, agrochemicals, and other organic compounds, making it a valuable building block in the production of drugs and pesticide products. Its significance in organic synthesis and potential role in creating novel bioactive molecules have positioned 3-chloro-4-isopropylpyridine as an essential component in both research and industrial applications.
Uses
Used in Pharmaceutical Industry:
3-Chloro-4-isopropylpyridine is utilized as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and improving the efficacy of existing ones. Its unique structure allows for the creation of diverse chemical entities with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 3-chloro-4-isopropylpyridine is employed as an intermediate for the synthesis of pesticides and other crop protection products. Its incorporation aids in the development of more effective and targeted pest control solutions.
Used in Organic Synthesis Research:
3-Chloro-4-isopropylpyridine is a vital component in organic synthesis research, where it is used to explore novel reactions and develop new synthetic pathways. Its presence in the literature as a potential key intermediate highlights its importance in advancing the field of organic chemistry.
Used in the Synthesis of Novel Bioactive Molecules:
3-Chloro-4-isopropylpyridine has been reported as a potential key intermediate in the synthesis of novel bioactive molecules. This application underscores its versatility and the potential for discovering new compounds with significant biological activity.
Check Digit Verification of cas no
The CAS Registry Mumber 90731-99-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,7,3 and 1 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 90731-99:
(7*9)+(6*0)+(5*7)+(4*3)+(3*1)+(2*9)+(1*9)=140
140 % 10 = 0
So 90731-99-0 is a valid CAS Registry Number.
90731-99-0Relevant articles and documents
Transition-metal-free BF3-mediated regioselective direct alkylation and arylation of functionalized pyridines using grignard or organozinc reagents
Chen, Quan,Du Jourdin, Xavier Mollat,Knochel, Paul
supporting information, p. 4958 - 4961 (2013/05/22)
A formal regioselective cross-coupling of various pyridines with alkyl and aryl groups can be achieved by a BF3·OEt2-mediated addition of Grignard or organozinc reagents to pyridines bearing various substituents (chloro, bromo, cyano, vinyl, phenyl, carbethoxy, nitro, etc.) followed by an oxidative aromatization mediated by chloranil. Good regioselectivity and wide functional group tolerance make this method very versatile for the preparation of polyfunctional pyridines. No transition-metal catalyst is required in these coupling reactions.
