90732-01-7

Basic information

• Product Name: 3-CHLORO-4-PHENYLPYRIDINE
• Synonyms: 3-CHLORO-4-PHENYLPYRIDINE
• CAS NO: 90732-01-7
• Molecular Formula: C₁₁H₈ClN
• Molecular Weight: 189.64
• Mol File: 90732-01-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 271.2 °C at 760 mmHg
• Flash Point: 143.9 °C
• Appearance: /
• Density: 1.186 g/cm³
• Vapor Pressure: 0.0109mmHg at 25°C
• Refractive Index: 1.588
• PKA: 3.12±0.18(Predicted)
• CAS DataBase Reference: 3-CHLORO-4-PHENYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-4-PHENYLPYRIDINE(90732-01-7)
• EPA Substance Registry System: 3-CHLORO-4-PHENYLPYRIDINE(90732-01-7)

Safety Data

• Hazardous Substances Data: 90732-01-7(Hazardous Substances Data)

Usage

General Description

3-Chloro-4-phenylpyridine is a chemical compound with the molecular formula C11H8ClN. It is a chlorinated derivative of pyridine, a six-membered ring consisting of five carbon atoms and one nitrogen atom. 3-CHLORO-4-PHENYLPYRIDINE is a pale yellow solid with a molecular weight of 191.64 g/mol. 3-Chloro-4-phenylpyridine is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is a versatile building block in organic chemistry and is often used in the production of various functional materials, such as liquid crystals and polymers.

InChI:InChI=1/C11H8ClN/c12-11-8-13-7-6-10(11)9-4-2-1-3-5-9/h1-8H

Upstream product

• 90731-95-6 3-Chloro-4-phenyl-4H-pyridine-1-carboxylic acid phenyl ester 
• 55934-00-4 3,4-dichloropyridine 
• 201230-82-2 carbon monoxide 
• 98-80-6 phenylboronic acid 
• 77332-79-7 3-chloro-4-iodopyridine 
• 626-60-8 3-Chloropyridine 
• 108-86-1 bromobenzene 
• 458532-90-6 3-chloro-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridine 
• 88912-27-0 3-chloro-isonicotinic acid 
• 71-43-2 benzene 
• 138823-75-3 3-Chloro-1-ethoxycarbonyl-pyridinium; chloride 
• 106-51-4 p-benzoquinone 

Relevant articles and documents

Mild, visible light-mediated decarboxylation of aryl carboxylic acids to access aryl radicals

Herein we present the first example of aryl radical formation via the visible light-mediated decarboxylation of aryl carboxylic acids using photoredox catalysis. This method constitutes a mild protocol for the decarboxylation of cheap and abundant aryl carboxylic acids and tolerates both electron-rich substrates and those lacking ortho-substitution. The in situ formation of an acyl hypobromite is proposed to prevent unproductive hydrogen atom abstraction and trapping of the intermediate aroyloxy radical, enabling mild decarboxylation.

Silver-catalyzed arylation of (hetero)arenes by oxidative decarboxylation of aromatic carboxylic acids

A long-standing challenge in Minisci reactions is achieving the arylation of heteroarenes by oxidative decarboxylation of aromatic carboxylic acids. To address this challenge, the silver-catalyzed intermolecular Minisci reaction of aromatic carboxylic acids was developed. With an inexpensive silver salt as a catalyst, this new reaction enables a variety of aromatic carboxylic acids to undergo decarboxylative coupling with electron-deficient arenes or heteroarenes regardless of the position of the substituents on the aromatic carboxylic acid, thus eliminating the need for ortho-substituted aromatic carboxylic acids, which were a limitation of previously reported methods.

A Pd(II)-catalyzed ring-expansion reaction of cyclic 2-azidoalcohol derivatives: Synthesis of azaheterocycles

(Chemical Equation Presented) A Pd(II)-catalyzed ring expansion-reaction of cyclic 2-azidoalcohol derivatives was found to proceed via an unprecedented C-C bond cleavage-C-N bond formation sequence, providing substituted azaheterocycles.