90733-18-9

Basic information

• Product Name: 2-Propyn-1-amine, N,N-bis(1-methylethyl)-3-phenyl-
• Synonyms: 1-di-isopropylamino-3-phenylprop-2-yne;N,N-diisopropyl-N-(3-phenyl-2-propynyl)amine;N,N-di(isopropyl)-3-phenylprop-2-ynylamine;N,N-diisopropyl-3-phenylprop-2-yn-1-amine;diisopropyl-(3-phenyl-prop-2-ynyl)-amine;N,N-diisopropyl-(3-phenyl-2-propynyl)amine;2-Propyn-1-amine,N,N-bis(1-methylethyl)-3-phenyl
• CAS NO: 90733-18-9
• Molecular Formula: C15H21N
• Molecular Weight: 215.338
• Mol File: 90733-18-9.mol
• Article Data: 30

Chemical Properties

• CAS DataBase Reference: 2-Propyn-1-amine, N,N-bis(1-methylethyl)-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propyn-1-amine, N,N-bis(1-methylethyl)-3-phenyl-(90733-18-9)
• EPA Substance Registry System: 2-Propyn-1-amine, N,N-bis(1-methylethyl)-3-phenyl-(90733-18-9)

Safety Data

• Hazardous Substances Data: 90733-18-9(Hazardous Substances Data)

Upstream product

• 591-50-4 iodobenzene 
• 6323-87-1 N,N-diisopropylprop-2-yn-1-amine 
• 50-00-0 formaldehyd 
• 108-18-9 diisopropylamine 
• 536-74-3 phenylacetylene 
• 298-12-4 Glyoxilic acid 
• 3332-08-9 2-isopropyliminopropane 
• 10342-97-9 N,N-diisopropylmethylamine 
• 932-88-7 1-iodo-2-phenylethyne 
• 75-09-2 dichloromethane 
• 13120-02-0 N,N-diisopropyl selenoformamide 

Downstream Products

• 1147845-89-3 (E)-[5-(tert-butyldimethylsilyl)-3-phenyl-2-penten-4-ynyl]diisopropylamine 
• 1147846-08-9 (E)-[2-benzylidene-4-(tert-butyldimethylsilyl)-3-butynyl]diisopropylamine 
• 2327-99-3 1-phenylpropadiene 

Relevant articles and documents

Glyoxylic Acid: A Carboxyl Group-Assisted Metal-Free Decarboxylative Reaction Toward Propargylamines

Readily available propargylamines are not only fundamental building blocks in organic synthesis, but also possess many prominent biological activities. A highly efficient, concise and environmentally benign decarboxylative reaction of glyoxylic acid monohydrate with secondary amines and alkynes has been elaborated, and a variety of propargylamines are delivered in moderate to good yields under metal-free conditions. A mechanism involving a carboxyl group that assists the reactivity of alkynes, which makes the procedure of Michael addition proceeded smoothly, has been proposed.

Synthesis and Application of Silylene-Stabilized Low-Coordinate Ag(I)-Arene Cationic Complexes

We report the first examples of N-heterocyclic silylene-stabilized monocoordinate Ag(I) cationic complexes weakly bound to the free arene rings (C6H6, C6Me6, and C7H8). Further, the application of these electrophilic Ag(I) complexes as catalysts has been investigated toward A3-coupling reactions, which afforded a series of propargylamines in good to excellent yields with low catalyst loading under a solvent-free condition (19 examples).

Recyclable Cu/C3N4 composite catalyzed AHA/A3 coupling reactions for the synthesis of propargylamines

The heterogeneous Cu/C3N4 catalyst was found to be efficient for the synthesis of propargylamines using a three-component coupling reaction of alkynes, CH2Cl2 and amines (AHA) without additional base. Moreover,