90747-65-2Relevant academic research and scientific papers
A new class of 5-HT2B antagonists possesses favorable potency, selectivity, and rat pharmacokinetic properties
Moss, Neil,Choi, Younggi,Cogan, Derek,Flegg, Adam,Kahrs, Andreas,Loke, Pui,Meyn, Orietta,Nagaraja, Raj,Napier, Spencer,Parker, Ashley,Thomas Peterson,Ramsden, Philip,Sarko, Christopher,Skow, Donna,Tomlinson, Josh,Tye, Heather,Whitaker, Mark
scheme or table, p. 2206 - 2210 (2009/12/07)
We have been exploring the potential of 5-HT2B antagonists as a therapy for chronic heart failure. To assess the potential of this therapeutic approach, we sought compounds possessing the following attributes: (a) potent and selective antagonis
Penicillanic acid derivatives
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, (2008/06/13)
6-Amidinopenicillanic acid derivatives wherein one of the nitrogen atoms of the amidino group is part of a heterocyclic ring having on a side chain an unsubstituted heterocyclic ring containing 2 to 3 nitrogen atoms, and being useful as an antibiotic.
