90762-27-9

Upstream product

• 17327-08-1 Methyl 3-acetamido-4,6-O-benzylidene-3-deoxy-α-D-glucopyranoside 
• 72523-35-4 methyl 3-acetamido-2,4,6-tri-O-acetyl-3-deoxy-α-D-mannopyranoside 
• 90706-18-6 methyl 3-acetamido-4,6-O-benzylidene-3-deoxy-2-O-mesyl-α-D-glucopyranoside 
• 2484-80-2 Acetic acid (2S,3S,4S,5S,6R)-4-acetylamino-5-hydroxy-6-hydroxymethyl-2-methoxy-tetrahydro-pyran-3-yl ester 
• 14086-88-5 N-((3S,4S,5S,6R)-2,3,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-4-yl)-acetamide 
• 90706-21-1 3-acetamido-3-deoxy-6-O-triphenylmethyl-D-mannose diethyl dithioacetal 
• 90706-22-2 3-acetamido-2,4,5-tri-O-benzyl-3-deoxy-D-mannose diethyl dithioacetal 
• 90706-25-5 (2S,3S,4R)-1-acetyl-3,4-dibenzyloxy-2-<(1S)-1-benzyloxy-2,2-bis(ethylthio)-ethyl>pyrrolidine 
• 98301-94-1 3-acetamido-1,2,4,6-tetra-O-acetyl-3-deoxy-α,β-D-mannopyranose 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 90706-24-4 (S)-((2S,3S,4R)-1-Acetyl-3,4-bis-benzyloxy-pyrrolidin-2-yl)-benzyloxy-acetaldehyde 
• 90706-19-7 Methyl 3-acetamido-3-deoxy-2-O-mesyl-α-D-glucopyranoside 
• 90706-23-3 3-acetamido-2,4,5-tri-O-benzyl-3-deoxy-6-O-tosyl-D-mannose diethyl dithioacetal 
• 22617-60-3 N-[(1S,2S,3R)-1-((S)-2,2-Bis-ethylsulfanyl-1-hydroxy-ethyl)-2,3,4-trihydroxy-butyl]-acetamide 

Downstream Products

• 90706-27-7 (2R,3S,4R)-1-acetyl-3,4-dibenzyloxy-2-<(1R)-1-benzyloxy-3-ethoxycarbonylpropyl>pyrrolidine 
• 72741-87-8 swainsonine 
• 90706-28-8 swainsonine tribenzylate 
• 107741-02-6 (1S,2R,8R,8aR)-1,2,8-tris(benzyloxy)hexahydroindolizin-5(1H)-one 

Relevant academic research and scientific papers

TOTAL SYNTHESIS OF (-)-SWAINSONINE, AN α-D-MANNOSIDASE INHIBITOR ISOLATED FROM Swainsona canescens

A newly isolated alkaloidal toxin, (-)-swainsonine , which exhibits an α-D-mannosidase inhibitory activity, has been synthesised stereoselectively in 15 steps starting from methyl 3-acetamido-2,4,6-tri-O-acetyl-3-deoxy-α-D-mannopyranoside.

TOTAL SYNTHESIS OF (-)-SWAINSONINE, AN α-MANNOSIDASE INHIBITOR ISOLATED FROM SWAINSONA CANESCENS

The alkaloidal toxin, (-)-swainsonine: (1S,2R,8R,8aR)-1,2,8-trihydroxyoctahydroindolizine has been synthesized stereoselectively starting from methyl 3-acetamido-2,4,6-tri-O-acetyl-3-deoxy-α-D-mannopyranoside in a 15 steps rection.