90766-75-9Relevant academic research and scientific papers
Butenolide annelation using a manganese(III) oxidation. A synthesis of 4-arylfuran-2(5H)-ones
Demir, Ayhan S.,Camkerten, Nurettin,Gercek, Zuhal,Duygu, Nese,Reis, Omer,Arikan, Elif
, p. 2441 - 2448 (2007/10/03)
A general procedure was developed for the annelation of a butenolide to an aromatic ketone that highlighted a manganese(III) oxidation of aromatic ketones. The oxidation of aromatic ketones with manganese(III) acetate in the presence of 2-bromoacetic acid or the Mn(II) salt of this carboxylic acid provided a regioselectively convenient synthesis of 2-(2-bromoacetoxy) ketones. An Arbuzov or Wittig reaction of 2-(2-bromoacetoxy) ketones followed by cyclisation furnished 4-arylfuran-2(5H)-ones in good yield.
