491876-40-5

Upstream product

• 50-00-0 formaldehyd 
• 90766-97-5 5-bromo-6-phenylpyridazin-3(2H)-one 

Downstream Products

• 2166-34-9 5,6-diphenylpyridazine-3-(2H)-one 
• 433330-64-4 5-(4-methoxyphenyl)-6-phenylpyridazin-3(2H)-one 
• 351416-13-2 5-(4-chloro-phenyl)-6-phenyl-2H-pyridazin-3-one 
• 1001620-03-6 (E)-3-(6-Oxo-3-phenyl-1,6-dihydro-pyridazin-4-yl)-acrylic acid methyl ester 
• 499783-15-2 6-phenyl-5-phenylthio-3(2H)-pyridazinone 
• 90766-97-5 5-bromo-6-phenylpyridazin-3(2H)-one 
• 404936-90-9 6-phenyl-5-(2-trimethylsilanylethynyl)-3(2H)-pyridazinone 
• 351416-15-4 4-(6-oxo-3-phenyl-1,6-dihydro-pyridazin-4-yl)-benzaldehyde 

Relevant academic research and scientific papers

Pyridazines. Part 36: Synthesis and antiplatelet activity of 5-substituted-6-phenyl-3(2H)-pyridazinones

A convenient and efficient palladium-catalysed retro-ene-assisted method has been developed to prepare a series of 5-substituted-6-phenyl-3(2H)- pyridazinones as potential antiplatelet drugs. The most active compounds were those that contain a 3-phenyl-3-

Pyridazines. Part 35: Traceless solid phase synthesis of 4,5- and 5,6-diaryl-3(2H)-pyridazinones

A new method for the traceless solid phase synthesis of 3(2H)-pyridazinones has been developed employing dihydropyran-functionalized resin. The procedure has permitted the preparation of several diarylpyridazinones through a Suzuki cross-coupling reaction and cleavage conditions that promoted a retro-ene fragmentation.

Pyridazines. Part 30:1 Palladium-catalysed synthesis of 5-substituted 6-phenyl-3(2H)-pyridazinones asissted by a retro-ene transformation

The efficient one-pot functionalization, through palladium-catalysed reactions, of position 5 of the 6-phenyl-3(2H)-pyridazinone system has been performed using a retro-ene-assisted fragmentation. This route allows access through a short synthetic sequenc