907945-69-1

Basic information

• Product Name: 6-BroMo-iMidazo[1,2-a]pyriMidine-2-carboxylic acid
• Synonyms: 6-BroMo-iMidazo[1,2-a]pyriMidine-2-carboxylic acid
• CAS NO: 907945-69-1
• Molecular Formula: C₇H₄BrN₃O₂
• Molecular Weight: 242.02956
• Mol File: 907945-69-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-BroMo-iMidazo[1,2-a]pyriMidine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-BroMo-iMidazo[1,2-a]pyriMidine-2-carboxylic acid(907945-69-1)
• EPA Substance Registry System: 6-BroMo-iMidazo[1,2-a]pyriMidine-2-carboxylic acid(907945-69-1)

Safety Data

• Hazardous Substances Data: 907945-69-1(Hazardous Substances Data)

Upstream product

• 944896-67-7 ethyl 6-bromoimidazo[1,2-a]pyrimidine-2-carboxylate 
• 7752-82-1 5-bromo-2-aminopyrimidine 
• 70-23-5 ethyl Bromopyruvate 

Downstream Products

• 907945-70-4 ethyl 6-(4-chlorophenyl)imidazo[1,2-a]pyrimidine-2-carboxylate 

Relevant articles and documents

PRMT5 INHIBITORS

The present invention provides a compound of Formula (I) and the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are PRMT5 inhibitors. Also provided are methods of making compounds of Formula I, pharmaceutical compositions comprising compounds of Formula I, and methods of using these compounds to treat cancer, sickle cell, and hereditary persistence of foetal hemoglobin (HPFH) mutations.