944896-67-7 Usage
Uses
Used in Pharmaceutical Industry:
Ethyl 6-bromoimidazo[1,2-a]pyrimidine-2-carboxylic acid is used as a key intermediate in the synthesis of pharmaceuticals for its potential role in creating biologically active molecules. It serves as a building block for the development of new drugs, particularly those with anticancer and antiviral properties, due to its unique chemical structure and reactivity.
Used in Agrochemical Industry:
In the field of agriculture, Ethyl 6-bromoimidazo[1,2-a]pyrimidine-2-carboxylic acid is used as a precursor in the development of new pesticides. Its potential applications in this industry stem from its ability to be incorporated into molecules with pesticidal activity, contributing to the creation of innovative and effective solutions for crop protection.
Used in Medicinal Chemistry Research:
Ethyl 6-bromoimidazo[1,2-a]pyrimidine-2-carboxylic acid is utilized as a research compound in medicinal chemistry. It aids scientists in understanding the structure-activity relationships of various biologically active molecules and contributes to the advancement of drug discovery by providing a foundation for the design and synthesis of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 944896-67-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,4,8,9 and 6 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 944896-67:
(8*9)+(7*4)+(6*4)+(5*8)+(4*9)+(3*6)+(2*6)+(1*7)=237
237 % 10 = 7
So 944896-67-7 is a valid CAS Registry Number.
944896-67-7Relevant academic research and scientific papers
PRMT5 INHIBITORS
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Page/Page column 107-108, (2021/06/26)
The present invention provides a compound of Formula (I) and the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are PRMT5 inhibitors. Also provided are methods of making compounds of Formula I, pharmaceutical compositions comprising compounds of Formula I, and methods of using these compounds to treat cancer, sickle cell, and hereditary persistence of foetal hemoglobin (HPFH) mutations.
HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS
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Paragraph 000189, (2019/06/11)
The compounds of Formula I, Formula Ia, and Formula Ib are described herein along with their analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites, and prodrugs thereof. These compounds inhibit PRMT5 and are useful as therpeautic or ameliorating agent for diseases that are involved in cellular growth such as malignant tumors, schizophrenia, Alzheimer's disease, Parkinson's disease and the like.
BICYCLIC PYRIDINE, PYRAZINE, AND PYRIMIDINE DERIVATIVES AS PI3K BETA INHIBITORS
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Page/Page column 100, (2018/01/19)
The present invention relates to bicyclic pyridine, pyrazine, and pyrimidine derivatives of Formula (I) wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as pI3Kβ inhibitors. The invention further relates to pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
